Recent advances in the pharmacological diversification of quinazoline/quinazolinone hybrids
Due to the pharmacological activities of quinazoline and quinazolinone scaffolds, it has
aroused great interest in medicinal chemists for the development of new drugs or drug …
aroused great interest in medicinal chemists for the development of new drugs or drug …
Comprehensive review in current developments of benzimidazole‐based medicinal chemistry
The properties of benzimidazole and its derivatives have been studied over more than one
hundred years. Benzimidazole derivatives are useful intermediates/subunits for the …
hundred years. Benzimidazole derivatives are useful intermediates/subunits for the …
Recent advances in the structural library of functionalized quinazoline and quinazolinone scaffolds: Synthetic approaches and multifarious applications
Drug development has been a principal driving force in the rapid maturation of the field of
medicinal chemistry during the past several decades. During this period, the intriguing and …
medicinal chemistry during the past several decades. During this period, the intriguing and …
Therapeutic evolution of benzimidazole derivatives in the last quinquennial period
Benzimidazole, a fused heterocycle bearing benzene and imidazole has gained
considerable attention in the field of contemporary medicinal chemistry. The moiety is of …
considerable attention in the field of contemporary medicinal chemistry. The moiety is of …
Pyrimidine: a review on anticancer activity with key emphasis on SAR
A Mahapatra, T Prasad, T Sharma - Future journal of pharmaceutical …, 2021 - Springer
Background Cancer is a global health challenge, it impacts the quality of life and its
treatment is associated with several side effects. Resistance of the cancer cells to the …
treatment is associated with several side effects. Resistance of the cancer cells to the …
An insight into the therapeutic potential of quinazoline derivatives as anticancer agents
I Ahmad - MedChemComm, 2017 - pubs.rsc.org
Cancer is one of the major causes of worldwide human mortality. A wide range of cytotoxic
drugs are available on the market, and several compounds are in different phases of clinical …
drugs are available on the market, and several compounds are in different phases of clinical …
Benzimidazole: A milestone in the field of medicinal chemistry
In the last 2-3 decades, the broad research in the application of benzimidazole derivatives
made it important for mankind. Many scientists have worked on benzimidazole derivatives …
made it important for mankind. Many scientists have worked on benzimidazole derivatives …
Benzimidazole scaffolds as promising antiproliferative agents: A review
Cancer is one of the most serious medical problem and second leading cause of death in
the world, characterized by a deregulation of the cell cycle which mainly results in a …
the world, characterized by a deregulation of the cell cycle which mainly results in a …
Design and synthesis of benzimidazole-chalcone derivatives as potential anticancer agents
Numerous reports have shown that conjugated benzimidazole derivatives possess various
kinds of biological activities, including anticancer properties. In this report, we designed and …
kinds of biological activities, including anticancer properties. In this report, we designed and …
Quinazoline derivatives as potential therapeutic agents in urinary bladder cancer therapy
P Wdowiak, J Matysiak, P Kuszta, K Czarnek… - Frontiers in …, 2021 - frontiersin.org
Cancer diseases remain major health problems in the world despite significant
developments in diagnostic methods and medications. Many of the conventional therapies …
developments in diagnostic methods and medications. Many of the conventional therapies …