Glycerol: a neglected variable in metabolic processes?

D Brisson, MC Vohl, J St‐Pierre, TJ Hudson… - …, 2001 - Wiley Online Library
Glycerol is a small and simple molecule produced in the breakdown of glucose, proteins,
pyruvate, triacylglycerols and other glycerolipid, as well as release from dietary fats. An …

Exploring thermal sensitivities and adaptations of oxidative phosphorylation pathways

H Lemieux, PU Blier - Metabolites, 2022 - mdpi.com
Temperature shifts are a major challenge to animals; they drive adaptations in organisms
and species, and affect all physiological functions in ectothermic organisms. Understanding …

Therapeutic Potential of Clove Essential Oil in Diabetes: Modulation of Pro‐Inflammatory Mediators, Oxidative Stress and Metabolic Enzyme Activities

I Nait Irahal, D Darif, I Guenaou, F Hmimid… - Chemistry & …, 2023 - Wiley Online Library
Type 1 diabetes is characterized by insulin deficiency due to the destruction of pancreatic β
cells, leading to hyperglycemia, which in turn induces vascular complications. In the current …

Syzygium aromaticum bud (clove) essential oil is a novel and safe aldose reductase inhibitor: in silico, in vitro, and in vivo evidence

IN Irahal, I Guenaou, FA Lahlou, F Hmimid, N Bourhim - Hormones, 2022 - Springer
Purpose This study aimed to evaluate the antioxidant and antidiabetic properties of clove
essential oil (CEO) and to elucidate its mode of action, using selected biochemical targets …

Glycerol 3-phosphate dehydrogenases (1 and 2) in cancer and other diseases

S Oh, XL Mai, J Kim, ACV de Guzman, JY Lee… - … & Molecular Medicine, 2024 - nature.com
The glycerol 3-phosphate shuttle (GPS) is composed of two different enzymes: cytosolic
NAD+-linked glycerol 3-phosphate dehydrogenase 1 (GPD1) and mitochondrial FAD-linked …

Integrated Redox-Metabolic Orchestration Sustains Life in Hibernating Ground Squirrels

A Jankovic, A Kalezic, A Korac, B Buzadzic… - Antioxidants & Redox …, 2024 - liebertpub.com
Significance: The ultimate manifestations of life, birth, survival under various environmental
pressures and death are based on bioenergetics. Hibernation is a unique survival strategy …

Structural and functional properties of glycerol-3-phosphate dehydrogenase from a mammalian hibernator

M de la Roche, SN Tessier, KB Storey - The Protein Journal, 2012 - Springer
Abstract Glycerol-3-phosphate dehydrogenase (G3PDH; EC 1.1. 1.8) was purified from liver
and skeletal muscle of black-tailed prairie dogs (Cynomys ludivicianus), a hibernating …

Purification and properties of glycerol-3-phosphate dehydrogenase from the liver of the hibernating ground squirrel, Urocitellus richardsonii

AA Ruberto, CL Childers, KB Storey - Comparative Biochemistry and …, 2016 - Elsevier
Abstract Cytosolic glycerol-3-phosphate dehydrogenase (G3PDH, EC 1.1. 1.8) is an
important branch point enzyme connecting lipid metabolism and carbohydrate metabolism …

Temperature and serine phosphorylation regulate glycerol-3-phosphate dehydrogenase in skeletal muscle of hibernating Richardson's ground squirrels

AA Ruberto, SM Logan… - Biochemistry and Cell …, 2019 - cdnsciencepub.com
Glycerol-3-phosphate dehydrogenase (G3PDH) bridges carbohydrate and lipid metabolism
by interconverting glycerol-3-phosphate (G3P) and dihydroxyacetone phosphate (DHAP) …

Purification and characterization of cytosolic glycerol-3-phosphate dehydrogenase from skeletal muscle of jerboa (Jaculus orientalis)

W Berrada, A Naya, A Iddar, N Bourhim - Molecular and cellular …, 2002 - Springer
Cytosolic glycerol-3-phosphate dehydrogenase was purified from jerboa (Jaculus orientalis)
skeletal muscle and its physical and kinetic properties investigated. The purification method …