Among the various bacterial infections, tuberculosis (TB) remains a life-threatening
infectious disease responsible as the most significant cause of mortality and morbidity …

Specific cell states in metazoans are established by the symphony of gene expression
programs that necessitate intricate synergic interactions between transcription factors and …

LKB1 (liver kinase B1) is a master regulator of several processes such as metabolism,
proliferation, cell polarity and immunity. About one third of non-small cell lung cancers …

Head and neck squamous cell carcinoma (HNSCC) is the 6th most common cancer
worldwide and incidence rates are continuing to rise globally. Patients often present with …

Background The protein kinase A (PKA)/cAMP response element-binding protein (CREB)
has been suggested to be related to the inhibition of the proliferation of non-small cell lung …

The optimal development of preovulatory follicles needs follicle-stimulating hormone (FSH).
Recent findings revealed that salt-inducible kinases (SIKs) inhibit FSH actions in humans …

Abstract Background Liver kinase B1 (LKB1) is frequently mutated in lung adenocarcinoma,
and its loss contributes to tumor progression. Methods To identify LKB1 downstream genes …

Fibrolamellar carcinoma (FLC) is a rare liver cancer that disproportionately affects
adolescents and young adults. Currently, no standard of care is available and there remains …

CREB-regulated transcription coactivator 1 (CRTC1) plays an important role in synaptic
plasticity, learning and long-term memory formation through regulation of neuronal activity …

Fibrolamellar carcinoma (FLC) is a rare liver cancer that primarily occurs in young adults
and usually presents at advanced stages with no known risk factors or serum biomarkers …