Dietary curcumin: correlation between bioavailability and health potential

M Dei Cas, R Ghidoni - Nutrients, 2019 - mdpi.com
The yellow pigment curcumin, extracted from turmeric, is a renowned polyphenol with a
broad spectrum of health properties such as antioxidant, anti-inflammatory, anti-cancer …

The therapeutic potential of curcumin: A review of clinical trials

B Salehi, Z Stojanović-Radić, J Matejić… - European journal of …, 2019 - Elsevier
Curcuma longa L., its derived extracts and even its major compound curcumin has a long
history of use and doubtless effectiveness, reported through increasingly detailed in vitro, ex …

Kinase-targeted cancer therapies: progress, challenges and future directions

KS Bhullar, NO Lagarón, EM McGowan, I Parmar… - Molecular cancer, 2018 - Springer
The human genome encodes 538 protein kinases that transfer a γ-phosphate group from
ATP to serine, threonine, or tyrosine residues. Many of these kinases are associated with …

Curcumin and health

M Pulido-Moran, J Moreno-Fernandez… - Molecules, 2016 - mdpi.com
Nowadays, there are some molecules that have shown over the years a high capacity to act
against relevant pathologies such as cardiovascular disease, neurodegenerative disorders …

Targeting the JAK/STAT signaling pathway using phytocompounds for cancer prevention and therapy

S Bose, S Banerjee, A Mondal, U Chakraborty… - Cells, 2020 - mdpi.com
Cancer is a prevalent cause of mortality around the world. Aberrated activation of Janus
kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway …

[HTML][HTML] Receptor tyrosine kinases and their signaling pathways as therapeutic targets of curcumin in cancer

S Sudhesh Dev, SA Zainal Abidin… - Frontiers in …, 2021 - frontiersin.org
Receptor tyrosine kinases (RTKs) are transmembrane cell-surface proteins that act as signal
transducers. They regulate essential cellular processes like proliferation, apoptosis …

Curcumin encapsulation in functional PLGA nanoparticles: A promising strategy for cancer therapies

F da Silva Feltrin, T Agner, C Sayer… - Advances in colloid and …, 2022 - Elsevier
Nanoparticles have emerged as promising drug delivery systems for the treatment of several
diseases. Novel cancer therapies have exploited these particles as alternative adjuvant …

The targets of curcumin

H Zhou, CS Beevers, S Huang - Current drug targets, 2011 - ingentaconnect.com
Curcumin (diferuloylmethane), an orange-yellow component of turmeric or curry powder, is a
polyphenol natural product isolated from the rhizome of the plant Curcuma longa. For …

The multifaceted role of curcumin in cancer prevention and treatment

MK Shanmugam, G Rane, MM Kanchi, F Arfuso… - Molecules, 2015 - mdpi.com
Despite significant advances in treatment modalities over the last decade, neither the
incidence of the disease nor the mortality due to cancer has altered in the last thirty years …

New insights into therapeutic activity and anticancer properties of curcumin

AK Panda, D Chakraborty, I Sarkar… - Journal of experimental …, 2017 - Taylor & Francis
Natural compounds obtained from plants are capable of garnering considerable attention
from the scientific community, primarily due to their ability to check and prevent the onset …