[HTML][HTML] Endoplasmic reticulum stress and unfolded protein response in cardiovascular diseases
Cardiovascular diseases (CVDs), such as ischaemic heart disease, cardiomyopathy,
atherosclerosis, hypertension, stroke and heart failure, are among the leading causes of …
atherosclerosis, hypertension, stroke and heart failure, are among the leading causes of …
[HTML][HTML] Metformin beyond an anti-diabetic agent: A comprehensive and mechanistic review on its effects against natural and chemical toxins
A Malaekeh-Nikouei, S Shokri-Naei… - Biomedicine & …, 2023 - Elsevier
In addition to the anti-diabetic effect of metformin, a growing number of studies have shown
that metformin has some exciting properties, such as anti-oxidative capabilities, anticancer …
that metformin has some exciting properties, such as anti-oxidative capabilities, anticancer …
[HTML][HTML] True or False? Alzheimer's disease is Type 3 Diabetes: Evidences from Bench to Bedside.
Y Peng, S Yao, Q Chen, H Jin, M Du, Y Xue… - Ageing research reviews, 2024 - Elsevier
Globally, Alzheimer's disease (AD) is the most widespread chronic neurodegenerative
disorder, leading to cognitive impairment, such as aphasia and agnosia, as well as mental …
disorder, leading to cognitive impairment, such as aphasia and agnosia, as well as mental …
AGEs-induced and endoplasmic reticulum stress/inflammation-mediated regulation of GLUT4 expression and atherogenesis in diabetes mellitus
M Passarelli, UF Machado - Cells, 2021 - mdpi.com
In recent decades, complex and exquisite pathways involved in the endoplasmic reticulum
(ER) and inflammatory stress responses have been demonstrated to participate in the …
(ER) and inflammatory stress responses have been demonstrated to participate in the …
Metformin a potential pharmacological strategy in late onset Alzheimer's disease treatment
SR Poor, M Ettcheto, A Cano, E Sanchez-Lopez… - Pharmaceuticals, 2021 - mdpi.com
Alzheimer's disease (AD) is one of the most devastating brain disorders. Currently, there are
no effective treatments to stop the disease progression and it is becoming a major public …
no effective treatments to stop the disease progression and it is becoming a major public …
Combined donepezil with astaxanthin via nanostructured lipid carriers effective delivery to brain for Alzheimer's disease in rat model
MK Shehata, AA Ismail, MA Kamel - International Journal of …, 2023 - Taylor & Francis
Introduction Donepezil (DPL), a specific acetylcholinesterase inhibitor, is used as a first-line
treatment to improve cognitive deficits in Alzheimer's disease (AD) and it might have a …
treatment to improve cognitive deficits in Alzheimer's disease (AD) and it might have a …
[HTML][HTML] Effect of metformin treatment on memory and hippocampal neurogenesis decline correlated with oxidative stress induced by methotrexate in rats
N Sritawan, K Suwannakot, S Naewla… - Biomedicine & …, 2021 - Elsevier
Metformin is currently used as a first-line drug to treat patients with type 2 diabetes. Previous
studies have demonstrated that metformin has antioxidant properties and reduces …
studies have demonstrated that metformin has antioxidant properties and reduces …
[HTML][HTML] Combined effect of metformin and gallic acid on inflammation, antioxidant status, endoplasmic reticulum (ER) stress and glucose metabolism in fructose-fed …
TO Obafemi, KF Jaiyesimi, AA Olomola… - Toxicology Reports, 2021 - Elsevier
Over time, diabetes patients usually need combination therapy involving two or more agents,
including phytonutrients to attain therapeutic targets. The purpose of this research is to …
including phytonutrients to attain therapeutic targets. The purpose of this research is to …
Comparison of malondialdehyde levels and superoxide dismutase activity in resveratrol and resveratrol/donepezil combination treatment groups in Alzheimer's …
The aim of this study was to determine the malondialdehyde (MDA) level and superoxide
dismutase (SOD) activity in colchicine induced Alzheimer's disease (AD), resveratrol (RS) …
dismutase (SOD) activity in colchicine induced Alzheimer's disease (AD), resveratrol (RS) …
Effects of antidiabetic agents on Alzheimer's disease biomarkers in experimentally induced hyperglycemic rat model by streptozocin
Background Alzheimer's disease is the most common cause of dementia in the elderly
population. It is characterized by the accumulation of amyloid β and intraneuronal …
population. It is characterized by the accumulation of amyloid β and intraneuronal …