[HTML][HTML] Striatin family proteins: the neglected scaffolds

GK Tanti, P Pandey, S Shreya, BP Jain - Biochimica et Biophysica Acta …, 2023 - Elsevier
The Striatin family of proteins constitutes Striatin, SG2NA, and Zinedin. Members of this
family of proteins act as a signaling scaffold due to the presence of multiple protein-protein …

Complete Chloroplast Genomes of Chlorophytum comosum and Chlorophytum gallabatense: Genome Structures, Comparative and Phylogenetic Analysis

JN Munyao, X Dong, JX Yang, EM Mbandi, VO Wanga… - Plants, 2020 - mdpi.com
The genus Chlorophytum includes many economically important species well-known for
medicinal, ornamental, and horticultural values. However, to date, few molecular genomic …

Sequencing and Structural Analysis of the Complete Chloroplast Genome of the Medicinal Plant Lycium chinense Mill

Z Yang, Y Huang, W An, X Zheng, S Huang, L Liang - Plants, 2019 - mdpi.com
Lycium chinense Mill, an important Chinese herbal medicine, is widely used as a dietary
supplement and food. Here the chloroplast (CP) genome of L. chinense was sequenced and …

In the Rat Midbrain, SG2NA and DJ-1 have Common Interactome, Including Mitochondrial Electron Transporters that are Comodulated Under Oxidative Stress

P Bisoyi, D Ratna, G Kumar, BN Mallick… - Cellular and Molecular …, 2023 - Springer
Scaffold proteins Striatin and SG2NA assemble kinases and phosphatases into the
signalling complexes called STRIPAK. Dysfunctional STRIPAKs cause cancer, cerebral …

Striatin plays a major role in angiotensin II-induced cardiomyocyte and cardiac hypertrophy in mice in vivo

JJ Cull, STE Cooper, HO Alharbi, SP Chothani… - Clinical …, 2024 - portlandpress.com
The three striatins (STRN, STRN3, STRN4) form the core of STR iatin-I nteracting P
hosphatase and K inase (STRIPAK) complexes. These place protein phosphatase 2A …

The profile of expression of the scaffold protein SG2NA (s) differs between cancer types and its interactome in normal vis-a-vis breast tumor tissues suggests its wide …

P Bisoyi, P Devi, K Besra, A Prasad, BP Jain… - Molecular and Cellular …, 2022 - Springer
Striatin and SG2NA are scaffold proteins that form signaling complexes called STRIPAK. It
has been associated with developmental abnormalities, cancer, and several other diseases …

SG2NA enhances cancer cell survival by stabilizing DJ-1 and thus activating Akt

GK Tanti, S Pandey, SK Goswami - Biochemical and Biophysical Research …, 2015 - Elsevier
SG2NA in association with striatin and zinedin forms a striatin family of WD-40 repeat
proteins. This family of proteins functions as scaffold in different signal transduction …

[HTML][HTML] SG2NA is a regulator of endoplasmic reticulum (ER) homeostasis as its depletion leads to ER stress

BP Jain, S Pandey, N Saleem, GK Tanti… - Cell Stress and …, 2017 - Elsevier
SG2NA belongs to a three-member striatin subfamily of WD40 repeat superfamily of
proteins. It has multiple protein-protein interaction domains involved in assembling …

GSK3β and ERK regulate the expression of 78 kDa SG2NA and ectopic modulation of its level affects phases of cell cycle

S Pandey, I Talukdar, BP Jain, GK Tanti… - Scientific Reports, 2017 - nature.com
Striatin and SG2NA are essential constituents of the multi-protein STRIPAK assembly
harbouring protein phosphatase PP2A and several kinases. SG2NA has several isoforms …

Ectopic expression of 35 kDa and knocking down of 78 kDa SG2NAs induce cytoskeletal reorganization, alter membrane sialylation, and modulate the markers of EMT

R Gupta, G Kumar, BP Jain, S Chandra… - Molecular and Cellular …, 2021 - Springer
SG2NA is a protein of the striatin family that organizes STRIPAK complexes. It has splice
variants expressing differentially in tissues. Its 78 kDa isoform regulates cell cycle, maintains …