Hesperidin has a protective effect on paclitaxel-induced testicular toxicity through regulating oxidative stress, apoptosis, inflammation and endoplasmic reticulum …
Paclitaxel (PTX) is widely used to treat a number of malignancies, although it has toxic side
effects. Hesperidin (HES) has a wide range of biological and pharmacological properties …
effects. Hesperidin (HES) has a wide range of biological and pharmacological properties …
[HTML][HTML] How hesperidin and Hesperetin, as promising food Supplements, combat cardiovascular Diseases: A systematic review from bench to bed
This investigation aims to determine how hesperidin and hesperetin, natural flavonoids
found abundantly in citrus fruits, affect cardiovascular diseases. From inception until January …
found abundantly in citrus fruits, affect cardiovascular diseases. From inception until January …
Chrysin mitigates diclofenac-induced hepatotoxicity by modulating oxidative stress, apoptosis, autophagy and endoplasmic reticulum stress in rats
Background Diclofenac (DF) is a non-steroidal anti-inflammatory drug (NSAID) generally
prescribed for the treatment of pain. In spite of the widespread use of DF, hepatotoxicity has …
prescribed for the treatment of pain. In spite of the widespread use of DF, hepatotoxicity has …
The protective effects of chrysin on cadmium-induced pulmonary toxicity; a multi-biomarker approach
This study aimed to determine the potential protective effects of chrysin (CHR) on
experimental cadmium (Cd)-induced lung toxicity in rats. To this end, rats were divided into …
experimental cadmium (Cd)-induced lung toxicity in rats. To this end, rats were divided into …
[HTML][HTML] Xanthomicrol: Effective therapy for cancer treatment
N Poormolaie, M Mohammadi, A Mir, M Asadi… - Toxicology Reports, 2023 - Elsevier
Cancer treatment is one of the main challenges of global health. For decades, researchers
have been trying to find anti-cancer compounds with minimal side effects. In recent years …
have been trying to find anti-cancer compounds with minimal side effects. In recent years …
Effect of syringic acid on oxidative stress, autophagy, apoptosis, inflammation pathways against testicular damage induced by lead acetate.
Background Heavy metals are one of the environmental pollutants. Lead (Pb) is one of the
most common of these heavy metals. In this study, it was aimed at investigating the effects of …
most common of these heavy metals. In this study, it was aimed at investigating the effects of …
[HTML][HTML] Lemon-derived nanovesicles achieve antioxidant and anti-inflammatory effects activating the AhR/Nrf2 signaling pathway
In the last years, extracellular vesicles (EVs) from different plant matrices have been isolated
and gained the interest of the scientific community for their intriguing biological properties. In …
and gained the interest of the scientific community for their intriguing biological properties. In …
Effects of chrysin in cadmium-induced testicular toxicity in the rat; role of multi-pathway regulation
SÇ Tuncer, S Küçükler, C Gür, S Aygörmez… - Molecular Biology …, 2023 - Springer
Abstract Background Cadmium (Cd) is a strong toxic agent and causes serious damage to
testicular tissues. Chrysin (CHR) is a natural flavonoid with many effective properties …
testicular tissues. Chrysin (CHR) is a natural flavonoid with many effective properties …
Smart Hesperidin/Chitosan Nanogel Mitigates Apoptosis and Endoplasmic Reticulum Stress in Fluoride and Aluminum-Induced Testicular Injury
NS Deiab, AS Kodous, MK Mahfouz, AM Said… - … Trace Element Research, 2024 - Springer
Fluoride and aluminum are ubiquitous toxic metals with adverse reproductive effects. The
citrus flavonoid hesperidin has protective activities but poor solubility and bioavailability …
citrus flavonoid hesperidin has protective activities but poor solubility and bioavailability …
Cyclosporine-induced kidney damage was halted by sitagliptin and hesperidin via increasing Nrf2 and suppressing TNF-α, NF-κB, and Bax
AM Abd-Eldayem, SM Makram, BAS Messiha… - Scientific Reports, 2024 - nature.com
Cyclosporine A (CsA) is employed for organ transplantation and autoimmune disorders.
Nephrotoxicity is a serious side effect that hampers the therapeutic use of CsA. Hesperidin …
Nephrotoxicity is a serious side effect that hampers the therapeutic use of CsA. Hesperidin …