C-glycosides are natural products with important biological activities but are recalcitrant to
degradation. Glycoside 3-oxidases (G3Oxs) are recently identified bacterial flavo-oxidases …

Human matrix metalloproteinase-1 (MMP-1) is a zinc (II)-dependent enzyme that catalyzes
collagenolysis. Despite the availability of extensive experimental data, the mechanism of …

Glycosyltransferases (GTs) are pivotal enzymes involved in glycosidic bond synthesis, which
can lead to either retention or inversion of the glycosyl moiety's anomeric configuration …

Biocatalytic C–H oxidation reactions are of important synthetic utility, provide a sustainable
route for selective synthesis of important organic molecules, and are an integral part of …

The specificity loop of Matrix Metalloproteinases (MMPs) is known to regulate recognition of
their substrates, and the S1′− site surrounded by the loop is a unique place to address the …

Collagen hydrolysis, catalyzed by Zn (II)-dependent matrix metalloproteinases (MMPs), is a
critical physiological process. Despite previous computational investigations into the …

The extracellular matrix is a complex system of interacting macromolecules that serve
structural and functional purposes to maintain homeostasis of a cell. These systems can …