[HTML][HTML] The immune microenvironment in cartilage injury and repair

M Li, H Yin, Z Yan, H Li, J Wu, Y Wang, F Wei, G Tian… - Acta Biomaterialia, 2022 - Elsevier
The ability of articular cartilage to repair itself is limited because it lacks blood vessels,
nerves, and lymph tissue. Once damaged, it can lead to joint swelling and pain, accelerating …

[HTML][HTML] Tendon injuries: Basic science and new repair proposals

F Wu, M Nerlich, D Docheva - EFORT open reviews, 2017 - eor.bioscientifica.com
Tendons connect muscles to bones, ensuring joint movement. With advanced age, tendons
become more prone to degeneration followed by injuries. Tendon repair often requires …

Regeneration of the rotator cuff tendon-to-bone interface using umbilical cord-derived mesenchymal stem cells and gradient extracellular matrix scaffolds from …

JH Yea, TS Bae, BJ Kim, YW Cho, CH Jo - Acta Biomaterialia, 2020 - Elsevier
Regeneration of the gradient structure of the tendon-to-bone interface (TBI) is a crucial goal
after rotator cuff repair. The purpose of this study was to investigate the efficacy of a …

Scaffold-and graft-based biological augmentation of rotator cuff repair: an updated systematic review and meta-analysis of preclinical and clinical studies for 2010 …

K Mandalia, A Mousad, B Welborn, O Bono… - Journal of Shoulder and …, 2023 - Elsevier
Background Despite advancements in the surgical techniques of rotator cuff repair (RCR),
there remains a high retear rate. Biological augmentation of repairs with overlaying grafts …

Decellularized xenografts in regenerative medicine: From processing to clinical application

H Capella‐Monsonís, DI Zeugolis - Xenotransplantation, 2021 - Wiley Online Library
Decellularized xenografts are an inherent component of regenerative medicine. Their
preserved structure, mechanical integrity and biofunctional composition have well …

Novel growth factor combination for improving rotator cuff repair: A rat in vivo study

M Zhu, M Lin Tay, KS Lim, SM Bolam… - … American Journal of …, 2022 - journals.sagepub.com
Background: The lack of healing at the repaired tendon-bone interface is an important cause
of failure after rotator cuff repair. While augmentation with growth factors (GFs) has …

Obesity impairs enthesis healing after rotator cuff repair in a rat model

SM Bolam, YE Park, S Konar… - … American Journal of …, 2021 - journals.sagepub.com
Background: Being overweight or obese is associated with poor outcomes and an increased
risk of failure after rotator cuff (RC) surgery. However, the effect of obesity on enthesis …

Decellularized human umbilical cord Wharton jelly scaffold improves tendon regeneration in a rabbit rotator cuff tendon defect model

Z Yuan, F Cao, C Gao, Z Yang… - The American journal …, 2022 - journals.sagepub.com
Background: Owing to limited self-healing capacity, failure of rotator cuff tendon healing is a
common complication after surgery. Biological scaffolds have garnered attention owing to …

[HTML][HTML] Rotator cuff repair with patch augmentation: what do we know?

TE Cobb, RAC Dimock, SD Memon… - Archives of Bone and …, 2022 - ncbi.nlm.nih.gov
Background: Repair of massive rotator cuff tears remains a challenging process with mixed
success. There is a growing interest in the use of patches to augment the repair construct …

Bridging repair of large rotator cuff tears using a multilayer decellularized tendon slices graft in a rabbit model

GM Liu, J Pan, Y Zhang, LJ Ning, JC Luo… - … : The Journal of …, 2018 - Elsevier
Purpose The purpose of this study was to evaluate the efficacy of an extracellular matrix
scaffold with multilayer decellularized tendon slices (MDTSs) for reconstructing large rotator …