Neuropathic pain is a debilitating condition characterized by abnormal signaling within the
nervous system, resulting in persistent and often intense sensations of pain. It can arise from …

This meta-analysis investigated the effect of oral gabapentinoids (ie, pregabalin and
gabapentin) on analgesic consumption (ie, primary outcome) and pain relief (ie, secondary …

Introduction The increasing number of gabapentinoid (pregabalin and gabapentin) harms,
including deaths observed across countries is concerning to health‐care professionals and …

Abstract α2δ proteins serve as auxiliary subunits of voltage-gated calcium channels, which
are essential components of excitable cells such as skeletal and heart muscles, nerve cells …

Background Gabapentinoids (gabapentin and pregabalin) are widely used in clinical
practice, but recent evidence indicates that they carry an increased risk of misuse. As …

OBJECTIVE: Gabapentinoids are gamma-aminobutyric acid analogue agents used in the
treatment of neuropathic pain. They are increasingly being abused to achieve euphoric and …

Background: The nonsurgical treatment of carpal tunnel syndrome (CTS) consists of multiple
modalities: splinting, corticosteroid injections, hand therapy, and oral medications. However …

Gabapentinoid drugs (pregabalin and gabapentin) have been successfully used in the
treatment of neuropathic pain and in focal seizure prevention. Recent research has …

Contex: Pregabalin is an anticonvulsant drug with analgesic activity for the treatment of
neuropathic pain. Aims: To valuate the toxicity of pregabalin in reproductive parameters …

Introduction Gabapentin is commonly prescribed as an off-label adjunct to opioids because
of its safer risk profile. Recent evidence has shown an increased risk of mortality when …