Platelets are the smallest blood cells, numbering 150 to 350× 10 9/L in healthy individuals.
The ability of activated platelets to adhere to an injured vessel wall and form aggregates was …

Microvesicles are members of the family of extracellular vesicles shed from the plasma
membrane of activated or apoptotic cells. Microvesicles were initially characterised by their …

Human platelets arise as subcellular fragments of megakaryocytes in bone marrow. The
physiologic demand, presence of disease such as cancer, or drug effects can regulate the …

Platelets play a central role in the arrest of bleeding after damage to a blood vessel and in
the development of thrombosis. Platelets rapidly respond after interaction with sub …

A large number of glycoprotein (GP) IIb/IIIa receptors are present on the surface of platelets.
Studies to define precisely the number of GPIIb/IIIa receptors using specific monoclonal …

When membrane-attached beads are pulled vertically by a laser tweezers, a membrane
tube of constant diameter (tether) is formed. We found that the force on the bead (tether …

We have developed a method for measuring the local concentration of ATP at the
extracellular surface of live cells. This method relies on the specific attachment to the cell …

Platelets are critical to hemostatic and immunological function, and are key players in cancer
progression, metastasis, and cancer-related thrombosis. Platelets interact with immune cells …

Platelets are the smallest of the many types of cells in circulating blood, averaging only 2.0
to 5.0 μm in diameter, 0.5 μm in thickness, and having a mean cell volume of 6 to 10 …

Platelets play an essential role in hemostasis through aggregation and adhesion to vascular
injury sites but their unnecessary activation can often lead to thrombotic diseases. Upon …