Integrative regulation of human brain blood flow

CK Willie, YC Tzeng, JA Fisher… - The Journal of …, 2014 - Wiley Online Library
Herein, we review mechanisms regulating cerebral blood flow (CBF), with specific focus on
humans. We revisit important concepts from the older literature and describe the interaction …

Neurovascular coupling in humans: physiology, methodological advances and clinical implications

AA Phillips, FHN Chan, MMZ Zheng… - Journal of Cerebral …, 2016 - journals.sagepub.com
Neurovascular coupling reflects the close temporal and regional linkage between neural
activity and cerebral blood flow. Although providing mechanistic insight, our understanding …

Cerebral blood flow during exercise: mechanisms of regulation

S Ogoh, PN Ainslie - Journal of applied physiology, 2009 - journals.physiology.org
The response of cerebral vasculature to exercise is different from other peripheral
vasculature; it has a small vascular bed and is strongly regulated by cerebral autoregulation …

Integration of cerebrovascular CO2 reactivity and chemoreflex control of breathing: mechanisms of regulation, measurement, and interpretation

PN Ainslie, J Duffin - American Journal of Physiology …, 2009 - journals.physiology.org
Cerebral blood flow (CBF) and its distribution are highly sensitive to changes in the partial
pressure of arterial CO2 (PaCO2). This physiological response, termed cerebrovascular …

[HTML][HTML] Human cardiovascular responses to passive heat stress

CG Crandall, TE Wilson - Comprehensive Physiology, 2015 - ncbi.nlm.nih.gov
Heat stress increases human morbidity and mortality compared to normothermic conditions.
Many occupations, disease states, as well as stages of life are especially vulnerable to the …

Autonomic control of cerebral blood flow: fundamental comparisons between peripheral and cerebrovascular circulations in humans

JL Koep, CE Taylor, JS Coombes… - The Journal of …, 2022 - Wiley Online Library
Understanding the contribution of the autonomic nervous system to cerebral blood flow
(CBF) control is challenging, and interpretations are unclear. The identification of calcium …

[HTML][HTML] Blood pressure regulation IX: cerebral autoregulation under blood pressure challenges

YC Tzeng, PN Ainslie - European journal of applied physiology, 2014 - Springer
Cerebral autoregulation (CA) is integral to the delicate process of maintaining stable
cerebral perfusion and brain tissue oxygenation against changes in arterial blood pressure …

Influence of changes in blood pressure on cerebral perfusion and oxygenation

SJE Lucas, YC Tzeng, SD Galvin, KN Thomas… - …, 2010 - Am Heart Assoc
Cerebral autoregulation (CA) is a critical process for the maintenance of cerebral blood flow
and oxygenation. Assessment of CA is frequently used for experimental research and in the …

Cardiovascular function in the heat‐stressed human

CG Crandall, J Gonzalez‐Alonso - Acta physiologica, 2010 - Wiley Online Library
Heat stress, whether passive (ie exposure to elevated environmental temperatures) or via
exercise, results in pronounced cardiovascular adjustments that are necessary for adequate …

[HTML][HTML] Relationship between cognitive function and regulation of cerebral blood flow

S Ogoh - The journal of physiological sciences, 2017 - Springer
Ageing is the primary risk factor for cognitive deterioration. Given that the cerebral blood flow
(CBF) or regulation of cerebral circulation is attenuated in the elderly, it could be expected …