Beware of docking!
YC Chen - Trends in pharmacological sciences, 2015 - cell.com
Docking is now routine in virtual screening or lead optimization for drug screening and
design. The number of papers related to docking has dramatically increased over the past …
design. The number of papers related to docking has dramatically increased over the past …
Recent Advances in the Construction of Phosphorus‐Substituted Heterocycles, 2009–2019
L Chen, XY Liu, YX Zou - Advanced Synthesis & Catalysis, 2020 - Wiley Online Library
Phosphorus‐substituted heterocycles represent an important class of organophosphorus
compounds, which not only widely exist in biologically active pharmaceuticals …
compounds, which not only widely exist in biologically active pharmaceuticals …
[HTML][HTML] Development of effective anti-influenza drugs: congeners and conjugates–a review
JJ Shie, JM Fang - Journal of Biomedical Science, 2019 - Springer
Influenza is a long-standing health problem. For treatment of seasonal flu and possible
pandemic infections, there is a need to develop new anti-influenza drugs that have good …
pandemic infections, there is a need to develop new anti-influenza drugs that have good …
High‐yielding synthesis of the anti‐influenza neuramidase inhibitor (−)‐oseltamivir by three “one‐pot” operations
H Ishikawa, T Suzuki, Y Hayashi - Angewandte Chemie, 2009 - Wiley Online Library
A great deal of attention has been paid both in the scientific literature and the general media
to the high potential risk of a worldwide spread of avian H5N1 influenza virus, the death rate …
to the high potential risk of a worldwide spread of avian H5N1 influenza virus, the death rate …
Asymmetric organocatalysis in total synthesis–a trial by fire
E Marqués-López, RP Herrera… - Natural Product …, 2010 - pubs.rsc.org
Covering: 2007 to 2009 This review covers the most recent applications of organocatalysis
in the synthesis of natural products and non-natural biologically active molecules. Our aim is …
in the synthesis of natural products and non-natural biologically active molecules. Our aim is …
Synthetic approaches to the neuraminidase inhibitors zanamivir (Relenza) and oseltamivir phosphate (Tamiflu) for the treatment of influenza
J Magano - Chemical reviews, 2009 - ACS Publications
Influenza, a severe viral infection of the respiratory system, is responsible for a significant
morbidity and mortality due to both annual epidemics and unpredictable pandemics. In the …
morbidity and mortality due to both annual epidemics and unpredictable pandemics. In the …
Ni (II)/Zn catalyzed reductive coupling of aryl halides with diphenylphosphine oxide in water
Ni(II)/Zn Catalyzed Reductive Coupling of Aryl Halides with Diphenylphosphine Oxide in Water |
Organic Letters ACS ACS Publications C&EN CAS Find my institution Log In Organic Letters …
Organic Letters ACS ACS Publications C&EN CAS Find my institution Log In Organic Letters …
Stereoselective Rh2(S-IBAZ)4-Catalyzed Cyclopropanation of Alkenes, Alkynes, and Allenes: Asymmetric Synthesis of Diacceptor Cyclopropylphosphonates and …
VNG Lindsay, D Fiset, PJ Gritsch, S Azzi… - Journal of the …, 2013 - ACS Publications
A mild and highly stereoselective rhodium (II)-catalyzed cyclopropanation of alkenes,
alkynes, and allenes with diacceptor diazo compounds is reported. Using the phosphonate …
alkynes, and allenes with diacceptor diazo compounds is reported. Using the phosphonate …
[HTML][HTML] Recent progress in chemical approaches for the development of novel neuraminidase inhibitors
Influenza virus is the main cause of an infectious disease called influenza affecting the
respiratory system including the throat, nose and lungs. Neuraminidase inhibitors are …
respiratory system including the throat, nose and lungs. Neuraminidase inhibitors are …
High‐yielding synthesis of the anti‐influenza neuraminidase inhibitor (−)‐oseltamivir by two “one‐pot” sequences
H Ishikawa, T Suzuki, H Orita… - … A European Journal, 2010 - Wiley Online Library
The efficient asymmetric total synthesis of (−)‐oseltamivir, an antiviral reagent, has been
accomplished by using two “one‐pot” reaction sequences, with excellent overall yield (60%) …
accomplished by using two “one‐pot” reaction sequences, with excellent overall yield (60%) …