Are Genetic Modifiers the Answer to Different Responses to Hydroxyurea Treatment?—A Pharmacogenetic Study in Sickle Cell Anemia Angolan Children

C Ginete, M Delgadinho, B Santos, V Pinto… - International Journal of …, 2023 - mdpi.com
Sickle cell anemia (SCA) is an inherited disease affecting the hemoglobin that is particularly
common in sub-Saharan Africa. Although monogenic, phenotypes are markedly …

Insights into myopic choroidal neovascularization based on quantitative proteomics analysis of the aqueous humor

H Yu, Z Zhong, Y Zhao, H Luo, J Sun, R Wang… - BMC genomics, 2023 - Springer
Background Previous studies on the biomarkers of pathologic myopia choroidal
neovascularization (pmCNV) development merely detected limited types of proteins and …

[HTML][HTML] Contribution of genetic polymorphism in ABCB1 to individual variations of imatinib plasma levels in patients with gastrointestinal stromal tumor

Y Ge, H Bai, A Mazzocca, J Zhang… - Journal of …, 2024 - ncbi.nlm.nih.gov
Background Imatinib mesylate (IM) is a first-line treatment option for the majority of patients
diagnosed with gastrointestinal stromal tumors (GISTs). Although the clinical benefit is high …

Polimorfismos genéticos asociados a la Respuesta de ranibizumab en neovascularización coroidea asociada a miopía magna

D Blánquez Martínez - 2023 - digibug.ugr.es
La miopía magna (MM) se ha asociado con un aumento del riesgo de sufrir complicaciones.
Sin embargo, es la miopía patológica (MP) en la que se produce un aumento excesivo de la …