Salmonella is a human and animal pathogen that causes gastro-enteric diseases. The key
to Salmonella infection is its entry into intestinal epithelial cells, where the bacterium resides …

In view of emerging drug-resistant tuberculosis (TB), host-directed adjunct therapies are
urgently needed to improve treatment outcomes with currently available anti-TB therapies …

Intracellular bacteria are responsible for many infectious diseases in humans and have
developed diverse mechanisms to interfere with host defense pathways. In particular …

Phagocytosis is an essential mechanism for immunity and homeostasis, performed by a
subset of cells known as phagocytes. Upon target engulfment, de novo formation of …

Shigella flexneri invades host cells by entering within a bacteria-containing vacuole (BCV).
In order to establish its niche in the host cytosol, the bacterium ruptures its BCV. Contacts …

To explore the potential roles of miRNAs in controlling the survival of mycobacteria in
macrophages, miR-17-5p in the regulation of Bacillus Calmette-Guérin (BCG) growth in the …

One-fourth of the global human population is estimated to be infected with strains of the
Mycobacterium tuberculosis complex (MTBC), the causative agent of tuberculosis (TB) …

Abstract Tumor Necrosis Factor Receptor 1 (TNF-R1) transmits various intracellular
signaling cascades leading to diverse biological outcomes, ranging from proliferation …

Large volumes of liquid and other materials from the extracellular environment are
internalised by eukaryotic cells via an endocytic process called macropinocytosis. It is now …

Phagocytosis is a critical biological activity through which the host can protect itself from
infectious and non-infectious environmental particles and remove unwanted host cells in …