Actions of symbiotic gut microbiota are in dynamic balance with the host's organism to
maintain homeostasis. Many different factors have an impact on this relationship, including …

Increasing evidence suggests that metabolites produced by the gut microbiota play a crucial
role in host–microbe interactions. Dietary tryptophan ingested by the host enters the gut …

Hematopoietic stem cell (HSC) aging is accompanied by hematopoietic reconstitution
dysfunction, including loss of regenerative and engraftment ability, myeloid differentiation …

Abstract Indoleamine 2, 3-dioxygenase 1 (IDO1) is activated in chronic inflammatory states,
eg, in the aging process and age-related diseases. IDO1 enzyme catabolizes L-tryptophan …

In recent decades, neuropsychiatric disorders such as major depressive disorder,
schizophrenia, bipolar, etc., have become a global health concern, causing various …

Abstract Ammonium perfluoro (2-methyl-3-oxahexanoate)(GenX), a replacement for
perfluorooctanoic acid (PFOA), has been detected in multiple environmental media and …

A wide variety of human diseases are associated with loss of microbial diversity in the
human gut, inspiring a great interest in the diagnostic or therapeutic potential of the …

The prevalence of obesity is a worldwide phenomenon in all age groups and is associated
with aging-related diseases such as type 2 diabetes, as well metabolic and cardiovascular …

Adzuki bean is widely consumed in East Asia. Although the positive effects of its biologically
active ingredients on obesity have been confirmed, the role of whole cooked adzuki bean in …

In the era of a steadily increasing lifespan, neurodegenerative diseases among the elderly
present a significant therapeutic and socio-economic challenge. A properly balanced diet …