Cyanobacteria were present on the earth 3.5 billion years ago; since then they have
colonized almost all terrestrial and aquatic ecosystems. They produce a high number of …

Cyclopeptides or cyclic peptides are polypeptides formed by ring closing of terminal amino
acids. A large number of natural cyclopeptides have been reported to be highly effective …

The organic anion transporting polypeptides (OATPs) are a superfamily of drug transporters
involved in the uptake and disposition of a wide array of structurally divergent endogenous …

Nowadays, effective cancer therapy is a global concern, and recent advances in
nanomedicine are crucial. Cancer is one of the major fatal diseases and a leading cause of …

Digestive system neoplasms are the leading causes of cancer-related death all over the
world. Solute carrier (SLC) superfamily is composed of a series of transporters that are …

Currently, chemotherapy is one of the mainstays of oncologic therapies. But the efficacy of
chemotherapy is often limited by drug resistance and severe side effects. Consequently, it is …

Cyanobacteria are photosynthetic microorganisms widely distributed in diverse
environments, including Antarctica, one of the most extreme ecosystems on the planet …

Microcystins, cyclic nonribosomal heptapeptides, are the most well-known cyanobacterial
toxins. They are exceptionally well studied, but open questions remain concerning their …

摘要目的: 探讨有机阴离子转运多肽1B3 (OATP1B3) 在肝细胞癌(肝癌) 组织中的表达及作用.
方法: 通过免疫组化实验和免疫印迹试验(Western blot) 检测肝癌组织及其癌旁组织中OATP1B3 …

In this study, we investigated the delivery of synthetic neurosteroids into MCF-7 human
breast adenocarcinoma cells via Organic Anionic Transporting Polypeptides (OATPs)(pH …