The Ebola virus (EBOV) is a filamentous virus that acquires its lipid envelope from the
plasma membrane of the host cell it infects. EBOV assembly and budding from the host cell …

Phosphatidylserine (PS) is a critical lipid factor in the assembly and spread of numerous
lipid‐enveloped viruses. Here, we describe the ability of the Ebola virus (EBOV) matrix …

The Ebola virus matrix protein VP40 mediates viral budding and negatively regulates viral
RNA synthesis. The mechanisms by which these two functions are exerted and regulated …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a lipid-enveloped virus
that acquires its lipid bilayer from the host cell it infects. SARS-CoV-2 can spread from cell to …

Plasma membrane (PM) domains and order phases have been shown to play a key role in
the assembly, release, and entry of several lipid-enveloped viruses. In the present study, we …

Viral proteins frequently undergo single or multiple amino acid mutations during replication,
which can significantly alter their functionality. The Ebola virus matrix protein VP40 is …

Ebola virus (EBOV) is a filamentous negative-sense RNA virus, which causes severe
hemorrhagic fever. There are limited vaccines or therapeutics for prevention and treatment …

The Ebola virus (EBOV) is a lipid‐enveloped virus with a negative sense RNA genome that
can cause severe and often fatal viral hemorrhagic fever. The assembly and budding of …

Rice black-streaked dwarf virus (RBSDV) is an important reovirus that infects both plants
and its transmission vector small brown planthopper, causing severe crop loss. High affinity …

The virion protein 40 (VP40) forms the viral matrix, mediates budding, and downregulates
viral RNA synthesis in ebolaviruses. In this issue of Structure, Werner et al. present a …