[HTML][HTML] Free fatty acid receptors in health and disease

I Kimura, A Ichimura, R Ohue-Kitano… - Physiological …, 2019 - journals.physiology.org
Fatty acids are metabolized and synthesized as energy substrates during biological
responses. Long-and medium-chain fatty acids derived mainly from dietary triglycerides, and …

[HTML][HTML] The protective role of butyrate against obesity and obesity-related diseases

S Coppola, C Avagliano, A Calignano, R Berni Canani - Molecules, 2021 - mdpi.com
Worldwide obesity is a public health concern that has reached pandemic levels. Obesity is
the major predisposing factor to comorbidities, including type 2 diabetes, cardiovascular …

Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes

L Zhao, F Zhang, X Ding, G Wu, YY Lam, X Wang, H Fu… - Science, 2018 - science.org
The gut microbiota benefits humans via short-chain fatty acid (SCFA) production from
carbohydrate fermentation, and deficiency in SCFA production is associated with type 2 …

[HTML][HTML] Impact of diet-modulated butyrate production on intestinal barrier function and inflammation

KE Bach Knudsen, HN Lærke, MS Hedemann… - Nutrients, 2018 - mdpi.com
A major challenge in affluent societies is the increase in disorders related to gut and
metabolic health. Chronic over nutrition by unhealthy foods high in energy, fat, and sugar …

[HTML][HTML] Short chain fatty acids in the colon and peripheral tissues: a focus on butyrate, colon cancer, obesity and insulin resistance

SM McNabney, TM Henagan - Nutrients, 2017 - mdpi.com
Increased dietary fiber consumption has been associated with many beneficial effects,
including amelioration of obesity and insulin resistance. These effects may be due to the …

Host microbiota constantly control maturation and function of microglia in the CNS

D Erny, AL Hrabě de Angelis, D Jaitin… - Nature …, 2015 - nature.com
As the tissue macrophages of the CNS, microglia are critically involved in diseases of the
CNS. However, it remains unknown what controls their maturation and activation under …

The contribution of gut bacterial metabolites in the human immune signaling pathway of non-communicable diseases

F Hosseinkhani, A Heinken, I Thiele… - Gut …, 2021 - Taylor & Francis
The interaction disorder between gut microbiota and its host has been documented in
different non-communicable diseases (NCDs) such as metabolic syndrome …

Towards a more comprehensive concept for prebiotics

LB Bindels, NM Delzenne, PD Cani… - Nature reviews …, 2015 - nature.com
The essential role of the gut microbiota for health has generated tremendous interest in
modulating its composition and metabolic function. One of these strategies is prebiotics …

[HTML][HTML] Gut microbiota as a potential target of metabolic syndrome: the role of probiotics and prebiotics

M He, B Shi - Cell & bioscience, 2017 - Springer
Metabolic syndrome (MS) comprises central obesity, increased plasma glucose levels,
hyperlipidemia and hypertension, and its incidence is increasing due to changes in lifestyle …

[HTML][HTML] The anti-inflammatory effects of short chain fatty acids on lipopolysaccharide-or tumor necrosis factor α-stimulated endothelial cells via activation of GPR41/43 …

M Li, BCAM Van Esch, PAJ Henricks… - Frontiers in …, 2018 - frontiersin.org
Background and Aim: Previously, we found that short chain fatty acids (SCFA) inhibit LPS or
TNFα-induced endothelial inflammatory responses and excessive vascular cell adhesion …