Synthesis of chalcones derivatives and their biological activities: a review

NAA Elkanzi, H Hrichi, RA Alolayan, W Derafa… - ACS …, 2022 - ACS Publications
Chalcone derivatives are considered valuable species because they possess a
ketoethylenic moiety, CO–CH═ CH–. Due to the presence of a reactive α, β-unsaturated …

[HTML][HTML] Pharmacological properties of chalcones: a review of preclinical including molecular mechanisms and clinical evidence

B Salehi, C Quispe, I Chamkhi, N El Omari… - Frontiers in …, 2021 - frontiersin.org
Chalcones are among the leading bioactive flavonoids with a therapeutic potential
implicated to an array of bioactivities investigated by a series of preclinical and clinical …

[HTML][HTML] Pharmacotherapeutics applications and chemistry of chalcone derivatives

JS Dhaliwal, S Moshawih, KW Goh, MJ Loy… - Molecules, 2022 - mdpi.com
Chalcones have been well examined in the extant literature and demonstrated antibacterial,
antifungal, anti-inflammatory, and anticancer properties. A detailed evaluation of the …

Secondary metabolites from hypocrealean entomopathogenic fungi: novel bioactive compounds

L Zhang, OE Fasoyin, I Molnár, Y Xu - Natural Product Reports, 2020 - pubs.rsc.org
Covering: 2014 up to the third quarter of 2019 Entomopathogens constitute a unique,
specialized trophic subgroup of fungi, most of whose members belong to the order …

Ultrasound promoted stereoselective synthesis of 2, 3-dihydrobenzofuran appended chalcones at ambient temperature

VA Adole, BS Jagdale, TB Pawar, AA Sagane - South african journal of …, 2020 - ajol.info
In the present investigation, an ultrasound promoted the synthesis of a series of (E)-3-(2, 3-
dihydrobenzofuran 5-yl)-1-(aryl) prop-2-en-1-one derivatives from 2, 3-dihydrobenzofuran-5 …

Novel pyrazine based anti-tubercular agents: Design, synthesis, biological evaluation and in silico studies

NW Hassan, MN Saudi, YS Abdel-Ghany, A Ismail… - Bioorganic …, 2020 - Elsevier
TB continues to be a leading health threat despite the availability of powerful anti-TB drugs.
We report herein the design and synthesis of various hybrid molecules comprising pyrazine …

Exploring bacterial interspecific interactions for discovery of novel antimicrobial compounds

O Tyc, VCL de Jager, M van den Berg… - Microbial …, 2017 - Wiley Online Library
Recent studies indicated that the production of secondary metabolites by soil bacteria can
be triggered by interspecific interactions. However, little is known to date about interspecific …

[HTML][HTML] Antioxidant activities of alkyl substituted pyrazine derivatives of chalcones—in vitro and in silico study

V Stepanić, M Matijašić, T Horvat, D Verbanac… - Antioxidants, 2019 - mdpi.com
Chalcones are polyphenolic secondary metabolites of plants, many of which have
antioxidant activity. Herein, a set of 26 synthetic chalcone derivatives with alkyl substituted …

[PDF][PDF] Chalcones bearing N, O, and S-heterocycles: Recent notes on their biological significances

B Ardiansah - Journal of Applied Pharmaceutical Science, 2019 - japsonline.com
Because of its relatively easy synthesis, chalcone skeleton has been as a point of interest for
organic and medicinal chemists from research groups worldwide. Chalcone scaffold …

[HTML][HTML] Synthesis, and biological screening of chloropyrazine conjugated benzothiazepine derivatives as potential antimicrobial, antitubercular and cytotoxic agents

AB Shaik, RR Bhandare, S Nissankararao… - Arabian Journal of …, 2021 - Elsevier
A series of twenty new chloropyrazine conjugated benzothiazepines (22–41) have been
synthesized with 58%–95% yields. The compounds were characterized by using different …