Interactions of SARS-CoV-2 with the blood–brain barrier

MA Erickson, EM Rhea, RC Knopp… - International Journal of …, 2021 - mdpi.com
Emerging data indicate that neurological complications occur as a consequence of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The blood–brain barrier …

Modern methods for delivery of drugs across the blood–brain barrier

Y Chen, L Liu - Advanced drug delivery reviews, 2012 - Elsevier
The blood–brain barrier (BBB) is a highly regulated and efficient barrier that provides a
sanctuary to the brain. It is designed to regulate brain homeostasis and to permit selective …

SARS-CoV-2 crosses the blood–brain barrier accompanied with basement membrane disruption without tight junctions alteration

L Zhang, L Zhou, L Bao, J Liu, H Zhu, Q Lv… - Signal transduction and …, 2021 - nature.com
SARS-CoV-2 has been reported to show a capacity for invading the brains of humans and
model animals. However, it remains unclear whether and how SARS-CoV-2 crosses the …

Neurological complications associated with the blood-brain barrier damage induced by the inflammatory response during SARS-CoV-2 infection

I Alquisiras-Burgos, I Peralta-Arrieta… - Molecular …, 2021 - Springer
The main discussion above of the novel pathogenic severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection has focused substantially on the immediate risks and …

Viral diseases of the central nervous system

PA Swanson II, DB McGavern - Current opinion in virology, 2015 - Elsevier
Highlights•A diverse spectrum of viruses can enter the CNS, causing acute and chronic
neurological disorders.•Virus-induced CNS diseases are influenced by routes of viral entry …

West Nile virus infection and immunity

MS Suthar, MS Diamond, M Gale Jr - Nature Reviews Microbiology, 2013 - nature.com
West Nile virus (WNV) is an emerging neurotropic flavivirus that is transmitted to humans
through the bite of an infected mosquito. WNV has disseminated broadly in the Western …

[HTML][HTML] What SARS-CoV-2 does to our brains

T Aschman, R Mothes, FL Heppner, H Radbruch - Immunity, 2022 - cell.com
Neurological symptoms in SARS-CoV-2-infected patients have been reported, but their
cause remains unclear. In theory, the neurological symptoms observed after SARS-CoV-2 …

Trafficking of immune cells in the central nervous system

EH Wilson, W Weninger… - The Journal of clinical …, 2010 - Am Soc Clin Investig
The CNS is an immune-privileged environment, yet the local control of multiple pathogens is
dependent on the ability of immune cells to access and operate within this site. However …

Viral infection of the central nervous system and neuroinflammation precede blood-brain barrier disruption during Japanese encephalitis virus infection

F Li, Y Wang, L Yu, S Cao, K Wang, J Yuan… - Journal of …, 2015 - Am Soc Microbiol
Japanese encephalitis is an acute zoonotic, mosquito-borne disease caused by Japanese
encephalitis virus (JEV). Japanese encephalitis is characterized by extensive inflammation …

Toxoplasma gondii: Entry, association, and physiological influence on the central nervous system

OA Mendez, AA Koshy - PLoS pathogens, 2017 - journals.plos.org
Toxoplasma gondii is one of the world's most successful parasites, in part because of its
ability to infect and persist in most warm-blooded animals. A unique characteristic of T …