Triosephosphate isomerase: a highly evolved biocatalyst
RK Wierenga, EG Kapetaniou… - Cellular and molecular life …, 2010 - Springer
Triosephosphate isomerase (TIM) is a perfectly evolved enzyme which very fast
interconverts dihydroxyacetone phosphate and d-glyceraldehyde-3-phosphate. Its catalytic …
interconverts dihydroxyacetone phosphate and d-glyceraldehyde-3-phosphate. Its catalytic …
Amyloid-β peptide nitrotyrosination stabilizes oligomers and enhances NMDAR-mediated toxicity
B Guivernau, J Bonet, V Valls-Comamala… - Journal of …, 2016 - Soc Neuroscience
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the pathological
aggregation of the amyloid-β peptide (Aβ). Monomeric soluble Aβ can switch from helicoidal …
aggregation of the amyloid-β peptide (Aβ). Monomeric soluble Aβ can switch from helicoidal …
Amyloid-β peptide fibrils induce nitro-oxidative stress in neuronal cells
G Ill-Raga, E Ramos-Fernández… - Journal of …, 2010 - journals.sagepub.com
Different mechanisms including oxidative stress are proposed for amyloid-β peptide (Aβ)
neurotoxicity, and here we contribute to demonstrate that nitro-oxidative stress is playing a …
neurotoxicity, and here we contribute to demonstrate that nitro-oxidative stress is playing a …
Methylglyoxal produced by amyloid-β peptide-induced nitrotyrosination of triosephosphate isomerase triggers neuronal death in Alzheimer's disease
M Tajes, A Eraso-Pichot… - Journal of …, 2014 - content.iospress.com
Amyloid-ß peptide (Aß) aggregates induce nitro-oxidative stress, contributing to the
characteristic neurodegeneration found in Alzheimer's disease (AD). One of the most …
characteristic neurodegeneration found in Alzheimer's disease (AD). One of the most …
Amyloid β accelerates phosphorylation of tau and neurofibrillary tangle formation in an amyloid precursor protein and tau double‐transgenic mouse model
Y Seino, T Kawarabayashi, Y Wakasaya… - Journal of …, 2010 - Wiley Online Library
In Alzheimer's disease, Aβ deposits are considered the initial cardinal events that induce
tauopathy secondarily. However, the relationship between Aβ amyloidosis and tauopathy …
tauopathy secondarily. However, the relationship between Aβ amyloidosis and tauopathy …
Induction of hemeoxygenase-1 expression after inhibition of hemeoxygenase activity promotes inflammation and worsens ischemic brain damage in mice
I Pérez-de-Puig, A Martín, R Gorina, X de la Rosa… - Neuroscience, 2013 - Elsevier
Hemeoxygenase (HO) is an enzymatic system that degrades heme. HO-1 is an inducible
isoform whereas HO-2 is constitutive. Stroke strongly induces HO-1 expression but the …
isoform whereas HO-2 is constitutive. Stroke strongly induces HO-1 expression but the …
[PDF][PDF] Methylglyoxal Produced by Amyloid-ß Peptide-Induced Nitrotyrosination of Triosephosphate Isomerase Triggers Neuronal Death in Alzheimer's Disease
M Tajesa, A Eraso-Pichota, F Rubio-Moscardóa… - academia.edu
Amyloid-ß peptide (Aß) aggregates induce nitro-oxidative stress, contributing to the
characteristic neurodegeneration found in Alzheimer's disease (AD). One of the most …
characteristic neurodegeneration found in Alzheimer's disease (AD). One of the most …
[引用][C] Amyloid-β peptide nitrotyrosination stabilizes oligomers and enhances NMDAR-mediated toxicity
B Guivernau Almazán… - … . 2016 Nov 16; 36 …, 2016 - Society for Neuroscience
[引用][C] Methylglyoxal produced by amyloid-β peptide-induced nitrotyrosination of triosephosphate isomerase triggers neuronal death in Alzheimer's disease
M Tajes Orduña, A Eraso Pichot… - Journal of Alzheimer's …, 2014 - IOS Press