Angiotensinogen (AGT) is one of the most significant enzymes of the renin-angiotensin-
aldosterone system (RAAS) which is involved in the regulation and maintenance of blood …

The renin-angiotensin system (RAS) is an essential hormonal system involved in water and
sodium reabsorption, renal blood flow regulation, and arterial constriction. Systemic …

In the last two decades, the study of the renin–angiotensin–aldosterone system (RAAS) has
revealed a counterregulatory protective axis. This protective arm is characterized by …

This study explores the extraction of polysaccharides from star anise (Illicium verum Hook. f.)
with its anti-obesity, antihypertensive, antidiabetic, and antioxidant properties. The aim is to …

Diabetic kidney disease (DKD) is a common microangiopathy in diabetic patients and the
main cause of death in diabetic patients. The main manifestations of DKD are proteinuria …

Diabetic nephropathy (DN) is the most common microvascular complication in diabetes and
one of the leading causes of end-stage renal disease. The standard treatments for patients …

G protein-coupled receptors (GPCRs) mediate cellular responses to diverse extracellular
stimuli that play vital roles in the regulation of biology, including behavior. Abnormal G …

The role of different G protein-coupled receptors (GPCRs) in the cardiovascular system is
well understood in cardiomyocytes and vascular smooth muscle cells (VSMCs). In the …

This review highlights the molecular basis of salt sensitivity in hypertension, with a focus on
the regulation of sodium transport in the distal nephron. Sodium reabsorption in this region …

Dysregulation of the renin-angiotensin system (RAS) is a contributor to high-fat diet-related
blood pressure (BP) increases. Deleterious effects of dysregulated RAS result in an …