This review is focused on the questions of why fish exhibit heat failure at thermal extremes
and which physiological mechanisms determine the acute upper thermal tolerance. We …

Biological membranes are complex and dynamic assemblies of lipids and proteins.
Poikilothermic organisms including bacteria, fungi, reptiles, and fish do not control their body …

Although giant unilamellar vesicles (GUVs) have been extensively studied as synthetic cell-
like microcompartments, their applicability as cytomimetic models is severely compromised …

Mixed lineage kinase domain-like protein (MLKL) was identified to function downstream of
receptor interacting protein 3 (RIP3) in tumor necrosis factor-α (TNF)-induced necrosis (also …

The design of compartmentalized colloids that exhibit biomimetic properties is providing
model systems for developing synthetic cell-like entities (protocells). Inspired by the cell …

Proper membrane physiology requires maintenance of biophysical properties, which must
be buffered from external perturbations. While homeostatic adaptation of membrane fluidity …

The interest of biologists in boron (B) has largely been focused on its role in plants for which
B was established as essential in 1923 (Warington, 1923 [153]). Evidence that B has a …

Sarcopenia is characterized by decreased skeletal muscle mass and function with age.
Aged muscles have altered lipid compositions; however, the role and regulation of lipids are …

Cells maintain membrane fluidity by regulating lipid saturation, but the molecular
mechanisms of this homeoviscous adaptation remain poorly understood. We have …

Spontaneous solute and solvent permeation through membranes is of vital importance to
human life, be it gas exchange in red blood cells, metabolite excretion, drug/toxin uptake, or …