It has been 12 yr since the publication of the last World Health Organization (WHO)
classification of tumours of the prostate and bladder. During this time, significant new …

Most epithelial tissues contain self-renewing stem cells that mature into downstream
progenies with increasingly limited differentiation potential. It is not surprising that cancers …

Background Fifty percent of patients with muscle–invasive bladder cancer (MI-BC) die from
their disease and current chemotherapy treatment only marginally increases survival. Novel …

Purpose: We aimed to validate and improve prognostic signatures for high-risk urothelial
carcinoma of the bladder. Experimental Design: We evaluated microarray data from 93 …

Transitional cell (urothelial) carcinoma of the bladder is the second most common urologic
malignancy and is one of the best understood neoplasms, with relatively well-defined …

Although urothelial carcinoma (UC) of the urinary bladder generally portends a favorable
prognosis, metastatic tumors often follow an aggressive clinical course. DNA was extracted …

The unprecedented advances in cancer genetics and genomics are rapidly affecting the
clinical management of solid tumors. Molecular diagnostics are now an integral part of …

CONTEXT: To present a summary of the 2nd International Consultation on Bladder Cancer
recommendations on the pathology of bladder cancer using an evidence-based strategy …

Survivin is an inhibitor of apoptosis protein (IAP) family member preferentially expressed in a
myriad of clinical cancers. The complex functional mechanism and regulatory roles of …

The determination of prognosis in bladder cancer is currently based on staging methods that
rely primarily on the pathological stage of a tumor with limited objective correlates. The …