Pathogenicity & virulence of Histoplasma capsulatum - A multifaceted organism adapted to intracellular environments

AF Valdez, DZ Miranda, AJ Guimarães, L Nimrichter… - Virulence, 2022 - Taylor & Francis
Histoplasmosis is a systemic mycosis caused by the thermally dimorphic fungus
Histoplasma capsulatum. Although healthy individuals can develop histoplasmosis, the …

The emerging role of extracellular vesicles in fungi: A double-edged sword

Y Lai, B Jiang, F Hou, X Huang, B Ling, H Lu… - Frontiers in …, 2023 - frontiersin.org
Fungi are eukaryotic microorganisms found in nature, which can invade the human body
and cause tissue damage, inflammatory reactions, organ dysfunctions, and diseases. These …

Cryptococcus extracellular vesicles properties and their use as vaccine platforms

J Rizzo, SSW Wong, AD Gazi… - Journal of …, 2021 - Wiley Online Library
Whereas extracellular vesicle (EV) research has become commonplace in different
biomedical fields, this field of research is still in its infancy in mycology. Here we provide a …

The paradoxical and still obscure properties of fungal extracellular vesicles

AC Piffer, D Kuczera, ML Rodrigues, L Nimrichter - Molecular Immunology, 2021 - Elsevier
Early compositional studies of fungal EVs revealed a complex combination of biomolecules,
including proteins, lipids, glycans, polysaccharides, nucleic acid and pigments, indicating …

Extracellular Vesicles from Candida haemulonii var. vulnera Modulate Macrophage Oxidative Burst

BTM Oliveira, TMH Dourado, PWS Santos… - Journal of Fungi, 2023 - mdpi.com
Members of the Candida haemulonii species complex are multidrug-resistant emergent
yeast pathogens able to cause superficial and invasive infections in risk populations. Fungal …

Structure, composition and biological properties of fungal extracellular vesicles

J Rizzo, A Taheraly, G Janbon - MicroLife, 2021 - academic.oup.com
Extracellular vesicles (EVs) are lipidic nanosized particles that deliver a highly complex
molecular cargo between cells and organisms and may serve numerous functions in …

The multiple frontiers in the study of extracellular vesicles produced by fungi

ML Rodrigues, RC May, G Janbon - Microbes and Infection, 2024 - Elsevier
The production of extracellular vesicles (EVs) by fungi has been recognized for about a
decade. Here we discuss the roles played by fungal EVs in biofilm formation, antifungal …

Extracellular Vesicles From Paracoccidioides brasiliensis Can Induce the Expression of Fungal Virulence Traits In Vitro and Enhance Infection in Mice

CE Octaviano, NE Abrantes, R Puccia - Frontiers in Cellular and …, 2022 - frontiersin.org
Extracellular vesicles (EVs) are cellular components involved in cargo delivery to the
extracellular environment, including the fungal cell wall. Their importance in cell–cell …

[HTML][HTML] From fundamental biology to the search for innovation: The story of fungal extracellular vesicles

ML Rodrigues, L Nimrichter - European Journal of Cell Biology, 2022 - Elsevier
Fungal extracellular vesicles (EVs) have attracted increased attention in recent years.
Originated from a serendipitous discovery, the initial observation of fungal EVs resulted in a …

Analysis of cryptococcal extracellular vesicles: experimental approaches for studying their diversity among multiple isolates, kinetics of production, methods of …

FCG Reis, B Gimenez, LJ Jozefowicz… - Microbiology …, 2021 - Am Soc Microbiol
Extracellular vesicles (EVs) produced by members of the Cryptococcus genus are
associated with fundamental processes of fungal physiology and virulence. However …