Cathepsin B Is Not an Intrinsic Factor Related to Asparaginase Resistance of the Acute Lymphoblastic Leukemia REH Cell Line

IM Costa, B Effer, TA Costa-Silva, C Chen… - International Journal of …, 2023 - mdpi.com
L-Asparaginase (ASNase) is a biopharmaceutical used as an essential drug in the treatment
of acute lymphoblastic leukemia (ALL). Yet, some cases of ALL are naturally resistant to …

Cysteine cathepsins and their prognostic and therapeutic relevance in leukemia

M Arora, G Pandey, SS Chauhan - Annals of the National …, 2021 - thieme-connect.com
Cysteine cathepsins are lysosomal proteases that require Cys-His ion pair in their catalytic
site for enzymatic activity. While their aberrant expression and oncogenic functions have …

Comprehensive chromosomal aberrations in a case of a patient with TCF3-HLF-positive BCP-ALL

M Lejman, M Włodarczyk, J Zawitkowska… - BMC Medical …, 2020 - Springer
Background The use of high-throughput analytical techniques has enabled the description
of acute lymphoblastic leukaemia (ALL) subtypes. The TCF3-HLF translocation is a very rare …

[PDF][PDF] Identification of regulatory networks and hub genes controlling mammary gland development and lactation in dairy goats during the late lactation, dry period …

R Xuan, T Chao, X Zhao, A Wang, Y Chu, Q Li, Y Zhao… - Review, 2020 - scholar.archive.org
Background From the late lactation to late gestation stages, the mammary gland tissue of
goats undergoes a process from involution to remodeling and then to high differentiation of …