[HTML][HTML] The basic characteristics of the pentraxin family and their functions in tumor progression

Z Wang, X Wang, H Zou, Z Dai, S Feng… - Frontiers in …, 2020 - frontiersin.org
The pentraxin is a superfamily of proteins with the same domain known as the pentraxin
domain at C-terminal. This family has two subgroups, namely; short pentraxins (C-reactive …

Understanding the molecular mechanism underlying the presynaptic toxicity of secreted phospholipases A2

J Pungerčar, I Križaj - Toxicon, 2007 - Elsevier
An important group of toxins, whose action at the molecular level is still a matter of debate, is
secreted phospholipases A2 (sPLA2s) endowed with presynaptic or β-neurotoxicity. The …

[图书][B] Animal lectins: form, function and clinical applications

GS Gupta - 2012 - books.google.com
Animal Lectins: Form, Function and Clinical Applications presents up-to-date knowledge of
animal lectins. Detailed descriptions on biological activities, tissue and/or subcellular …

A comprehensive analysis of immune infiltration in the tumor microenvironment of osteosarcoma

H Yang, L Zhao, Y Zhang, FF Li - Cancer Medicine, 2021 - Wiley Online Library
Background Even though immunotherapy has been an effective treatment for solid tumors,
its efficacy in osteosarcoma remains sub‐optimal. It is therefore imperative to understand the …

Apoptosis of human hepatocellular carcinoma cell (HepG2) induced by cardiotoxin III through S-phase arrest

X Chen, P Lv, J Liu, K Xu - Experimental and toxicologic pathology, 2009 - Elsevier
Cytotoxin III (CTX III), a basic polypeptide with 60 amino acid residues isolated from Naja
naja atra venom, have potential therapeutic activity in tumor therapy. However, the …

Inhibition of Hep2 and HeLa cell proliferation in vitro and EAC tumor growth in vivo by Lapemis curtus (Shaw 1802) venom

R Karthikeyan, S Karthigayan, MS Balasubashini… - Toxicon, 2008 - Elsevier
The antitumor activity of the sea snake venom (Lapemis curtus) was evaluated against
Ehrlich's ascites carcinoma (EAC) in Swiss albino mice and HeLa and Hep2 tumor cell …

[PDF][PDF] Antiproliferative effects of snake venom phospholipases A2 and their perspectives for cancer treatment

AV Osipov, YN Utkin - … ; Gopalakrishnakone, P., Cruz, L., Luo, S., Eds, 2017 - academia.edu
Secretory phospholipases A2 (PLA2s) are ubiquitous enzymes taking part in different
biological pathways including cell growth and differentiation. Mammalian PLA2s mostly …

Calcium‐stimulated mitogen‐activated protein kinase activation elicits Bcl‐xL downregulation and Bak upregulation in notexin‐treated human neuroblastoma SK‐N …

KC Chen, WH Liu, PH Kao… - Journal of cellular …, 2010 - Wiley Online Library
Notechis scutatus scutatus notexin induced apoptotic death of SK‐N‐SH cells accompanied
with downregulation of Bcl‐xL, upregulation of Bak, mitochondrial depolarization, and ROS …

The anti-cancer effect of Echis coloratus and Walterinnesia aegyptia venoms on colon cancer cells

M Daghestani, HH Hakami, ZK Hassan, G Badr… - Toxin reviews, 2021 - Taylor & Francis
Colorectal cancer (CRC) is one of the most prevalent causes of cancer mortality worldwide.
Saudi patients are more likely to present CRC at advanced disease stages and at younger …

Pentraxins: the L-type lectins and the C-reactive protein as a cardiovascular risk

GS Gupta, GS Gupta - Animal lectins: form, function and clinical …, 2012 - Springer
The pentraxins (PTX) are a superfamily of plasma proteins that are involved in innate
immunity in invertebrates and vertebrates. They contain L-type lectin folds and require Ca 2+ …