Endotypes of chronic rhinosinusitis: relationships to disease phenotypes, pathogenesis, clinical findings, and treatment approaches
Chronic rhinosinusitis (CRS) is a common clinical syndrome that produces significant
morbidity and costs to our health system. The study of CRS has progressed from an era …
morbidity and costs to our health system. The study of CRS has progressed from an era …
Contemporary classification of chronic rhinosinusitis beyond polyps vs no polyps: a review
Importance Chronic rhinosinusitis (CRS) is a broadly defined process that has previously
been used to describe many different sinonasal pathologic conditions from odontogenic …
been used to describe many different sinonasal pathologic conditions from odontogenic …
Use of endotypes, phenotypes, and inflammatory markers to guide treatment decisions in chronic rhinosinusitis
Objective With the advent of new treatment options for Chronic Rhinosinusitis (CRS) comes
the ability for physicians to provide more individualized patient care. Physicians are now …
the ability for physicians to provide more individualized patient care. Physicians are now …
Estimating COVID-19 infection and severity risks in patients with chronic rhinosinusitis: a Korean nationwide cohort study
Background Basic studies suggest that severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection can affect chronic rhinosinusitis (CRS), but there is unclear real …
(SARS-CoV-2) infection can affect chronic rhinosinusitis (CRS), but there is unclear real …
Clinically relevant phenotypes in chronic rhinosinusitis
JW Grayson, M Cavada… - Journal of Otolaryngology …, 2019 - journals.sagepub.com
Background Chronic rhinosinusitis (CRS) is a complex disease that incorporates many
different conditions. Currently, primary CRS is considered a disease of broad airway …
different conditions. Currently, primary CRS is considered a disease of broad airway …
Neutrophil extracellular traps in airway diseases: Pathological roles and therapeutic implications
A Jo, DW Kim - International Journal of Molecular Sciences, 2023 - mdpi.com
Neutrophils are important effector cells of the innate immune response that fight pathogens
by phagocytosis and degranulation. Neutrophil extracellular traps (NETs) are released into …
by phagocytosis and degranulation. Neutrophil extracellular traps (NETs) are released into …
Highlights in the advances of chronic rhinosinusitis
X Xu, S Reitsma, DY Wang, WJ Fokkens - Allergy, 2021 - Wiley Online Library
Chronic rhinosinusitis (CRS) is a complex upper airway inflammatory disease with a broad
spectrum of clinical variants. As our understanding of the disease pathophysiology evolves …
spectrum of clinical variants. As our understanding of the disease pathophysiology evolves …
Inflammatory heterogeneity in aspirin-exacerbated respiratory disease
Background Aspirin-exacerbated respiratory disease (AERD) is a mechanistically distinct
subtype of chronic rhinosinusitis with nasal polyps (CRSwNP). Although frequently …
subtype of chronic rhinosinusitis with nasal polyps (CRSwNP). Although frequently …
Current insight into treatment of chronic rhinosinusitis: phenotypes, endotypes, and implications for targeted therapeutics
N Chapurin, J Wu, AB Labby, RK Chandra… - Journal of Allergy and …, 2022 - Elsevier
Chronic rhinosinusitis is characterized by persistent locoregional mucosal inflammation of
the paranasal sinuses and upper airway that has substantial associated health care costs …
the paranasal sinuses and upper airway that has substantial associated health care costs …
Management of chronic rhinosinusitis with nasal polyposis in the era of biologics
Purpose of Review Chronic rhinosinusitis with nasal polyposis (CRSwNP) is a phenotypic
designation of the broader condition of chronic rhinosinusitis. The advent of targeted …
designation of the broader condition of chronic rhinosinusitis. The advent of targeted …