[HTML][HTML] The world of stable ribonucleoproteins and its mapping with Grad-seq and related approaches
Macromolecular complexes of proteins and RNAs are essential building blocks of cells.
These stable supramolecular particles can be viewed as minimal biochemical units whose …
These stable supramolecular particles can be viewed as minimal biochemical units whose …
[HTML][HTML] Dissecting monomer-dimer equilibrium of an RNase P protein provides insight into the synergistic flexibility of 5'leader pre-tRNA recognition
Ribonuclease P (RNase P) is a universal RNA-protein endonuclease that catalyzes
5'precursor-tRNA (ptRNA) processing. The RNase P RNA plays the catalytic role in ptRNA …
5'precursor-tRNA (ptRNA) processing. The RNase P RNA plays the catalytic role in ptRNA …
Structural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNA s
Viral suppressors of RNA silencing (VSRS s) are a diverse group of viral proteins that have
evolved to disrupt eukaryotic RNA silencing pathways, thereby contributing to viral …
evolved to disrupt eukaryotic RNA silencing pathways, thereby contributing to viral …
Long noncoding RNAs in cardiovascular disease
LM Holdt, A Kohlmaier, D Teupser - Genetic Causes of Cardiac Disease, 2019 - Springer
Recent advances in high-throughput sequencing of nucleic acids have led to the fascinating
insight that the majority of the human genome is transcribed. This includes tens of thousands …
insight that the majority of the human genome is transcribed. This includes tens of thousands …
NMR resonance assignments of RNase P protein from Thermotoga maritima
Abstract Ribonuclase P (RNase P) is an essential metallo-endonuclease that catalyzes 5′
precursor-tRNA (ptRNA) processing and exists as an RNA-based enzyme in bacteria …
precursor-tRNA (ptRNA) processing and exists as an RNA-based enzyme in bacteria …
Long Noncoding RNAs in Cardiovascular
LM Holdt, A Kohlmaier, D Teupser - Genetic Causes of Cardiac, 2019 - Springer
Recent advances in high-throughput sequencing of nucleic acids have led to the fascinating
insight that the majority of the human genome is transcribed. This includes tens of thousands …
insight that the majority of the human genome is transcribed. This includes tens of thousands …
RNA Recognition by the Histone Demethylase LSD1 and Proteinaceous RNase P: Characterization of the Binding of Highly Structured RNAs by Enzyme Complexes
WJ Martin - 2018 - ir.vanderbilt.edu
This study investigates the recognition of structured RNAs by two essential enzymes,
proteinaceous RNase P (PRORP) and lysine-specific demethylase-1 (LSD1). PRORP binds …
proteinaceous RNase P (PRORP) and lysine-specific demethylase-1 (LSD1). PRORP binds …
Towards Guiding Principles for Targeting RNA: Rational Approaches to Design and Synthesize RNA-Biased Small Molecule Libraries
BS Morgan - 2018 - search.proquest.com
RNA is increasingly recognized as a therapeutic target in many diseases, including viral and
bacterial infections, neurodegenerative disease, and cancer. Despite this, no FDA-approved …
bacterial infections, neurodegenerative disease, and cancer. Despite this, no FDA-approved …