Consensus report: definition and interpretation of remission in type 2 diabetes

MC Riddle, WT Cefalu, PH Evans… - The Journal of …, 2022 - academic.oup.com
Improvement of glucose levels into the normal range can occur in some people living with
diabetes, either spontaneously or after medical interventions, and in some cases can persist …

Emerging targets in type 2 diabetes and diabetic complications

S Demir, PP Nawroth, S Herzig… - Advanced …, 2021 - Wiley Online Library
Type 2 diabetes is a metabolic, chronic disorder characterized by insulin resistance and
elevated blood glucose levels. Although a large drug portfolio exists to keep the blood …

Update on prevention of cardiovascular disease in adults with type 2 diabetes mellitus in light of recent evidence: a scientific statement from the American Heart …

CS Fox, SH Golden, C Anderson, GA Bray, LE Burke… - Circulation, 2015 - Am Heart Assoc
Cardiovascular disease risk factor control as primary prevention in patients with type 2
diabetes mellitus has changed substantially in the past few years. The purpose of this …

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta …

E Wheeler, A Leong, CT Liu, MF Hivert… - PLoS …, 2017 - journals.plos.org
Background Glycated hemoglobin (HbA1c) is used to diagnose type 2 diabetes (T2D) and
assess glycemic control in patients with diabetes. Previous genome-wide association …

Type 2 diabetes in the real world: the elusive nature of glycemic control

SV Edelman, WH Polonsky - Diabetes care, 2017 - Am Diabetes Assoc
Despite US Food and Drug Administration (FDA) approval of over 40 new treatment options
for type 2 diabetes since 2005, the latest data from the National Health and Nutrition …

Diabetes in midlife and cognitive change over 20 years: a cohort study

AM Rawlings, AR Sharrett, ALC Schneider… - Annals of internal …, 2014 - acpjournals.org
Background: Type 2 diabetes is associated with dementia risk, but evidence is limited for
possible associations of diabetes and prediabetes with cognitive decline. Objective: To …

Intensive glycaemic control for patients with type 2 diabetes: systematic review with meta-analysis and trial sequential analysis of randomised clinical trials

B Hemmingsen, SS Lund, C Gluud, A Vaag, T Almdal… - Bmj, 2011 - bmj.com
Objective To assess the effect of targeting intensive glycaemic control versus conventional
glycaemic control on all cause mortality and cardiovascular mortality, non-fatal myocardial …

Health disparities in endocrine disorders: biological, clinical, and nonclinical factors—an Endocrine Society scientific statement

SH Golden, A Brown, JA Cauley… - The Journal of …, 2012 - academic.oup.com
Objective: The aim was to provide a scholarly review of the published literature on
biological, clinical, and nonclinical contributors to race/ethnic and sex disparities in …

Cardiovascular and kidney outcomes across the glycemic spectrum: insights from the UK Biobank

MC Honigberg, SM Zekavat, JP Pirruccello… - Journal of the American …, 2021 - jacc.org
Background Treatment guidelines for prediabetes primarily focus on glycemic control and
lifestyle management. Few evidence-based cardiovascular and kidney risk-reduction …

[HTML][HTML] Iron aggravates hepatic insulin resistance in the absence of inflammation in a novel db/db mouse model with iron overload

S Altamura, K Müdder, A Schlotterer, T Fleming… - Molecular …, 2021 - Elsevier
Objective The molecular pathogenesis of late complications associated with type 2 diabetes
mellitus (T2DM) is not yet fully understood. While high glucose levels indicated by increased …