Calcitonin gene-related peptide: physiology and pathophysiology
FA Russell, R King, SJ Smillie, X Kodji… - Physiological …, 2014 - journals.physiology.org
Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide. Discovered 30
years ago, it is produced as a consequence of alternative RNA processing of the calcitonin …
years ago, it is produced as a consequence of alternative RNA processing of the calcitonin …
[HTML][HTML] Blocking CGRP in migraine patients–a review of pros and cons
M Deen, E Correnti, K Kamm, T Kelderman… - The journal of headache …, 2017 - Springer
Migraine is the most prevalent neurological disorder worldwide and it has immense
socioeconomic impact. Currently, preventative treatment options for migraine include drugs …
socioeconomic impact. Currently, preventative treatment options for migraine include drugs …
Transdermal cannabidiol reduces inflammation and pain‐related behaviours in a rat model of arthritis
DC Hammell, LP Zhang, F Ma… - … journal of pain, 2016 - Wiley Online Library
Background Current arthritis treatments often have side‐effects attributable to active
compounds as well as route of administration. Cannabidiol (CBD) attenuates inflammation …
compounds as well as route of administration. Cannabidiol (CBD) attenuates inflammation …
The biopsychosocial approach to chronic pain: scientific advances and future directions.
The prevalence and cost of chronic pain is a major physical and mental health care problem
in the United States today. As a result, there has been a recent explosion of research on …
in the United States today. As a result, there has been a recent explosion of research on …
Vascular actions of calcitonin gene-related peptide and adrenomedullin
SD Brain, AD Grant - Physiological reviews, 2004 - journals.physiology.org
This review summarizes the receptor-mediated vascular activities of calcitonin gene-related
peptide (CGRP) and the structurally related peptide adrenomedullin (AM). CGRP is a 37 …
peptide (CGRP) and the structurally related peptide adrenomedullin (AM). CGRP is a 37 …
[HTML][HTML] Intermedin is a calcitonin/calcitonin gene-related peptide family peptide acting through the calcitonin receptor-like receptor/receptor activity-modifying protein …
J Roh, CL Chang, A Bhalla, C Klein, SYT Hsu - Journal of Biological …, 2004 - ASBMB
Calcitonin, calcitonin gene-related peptide (CGRP), adrenomedullin (ADM), and amylin
belong to a unique group of peptide hormones important for homeostasis in diverse tissues …
belong to a unique group of peptide hormones important for homeostasis in diverse tissues …
Anti‐inflammatory actions of acupuncture
FJ Zijlstra, I van den Berg-de Lange… - Mediators of …, 2003 - Wiley Online Library
Acupuncture has a beneficial effect when treating many diseases and painful conditions,
and therefore is thought to be useful as a complementary therapy or to replace generally …
and therefore is thought to be useful as a complementary therapy or to replace generally …
The role of peptides in central sensitization
VS Seybold - Sensory Nerves, 2009 - Springer
Peptides released in the spinal cord from the central terminals of nociceptors contribute to
the persistent hyperalgesia that defines the clinical experience of chronic pain. Using …
the persistent hyperalgesia that defines the clinical experience of chronic pain. Using …
Beyond CGRP: The calcitonin peptide family as targets for migraine and pain
The CGRP system has emerged as a key pharmacological target for the treatment of
migraine. However, some individuals who suffer from migraine have low or no response to …
migraine. However, some individuals who suffer from migraine have low or no response to …
[HTML][HTML] The role of inflammation, hypoxia, and opioid receptor expression in pain modulation in patients suffering from obstructive sleep apnea
Obstructive sleep apnea (OSA) is a relatively common disease in the general population.
Besides its interaction with many comorbidities, it can also interact with potentially painful …
Besides its interaction with many comorbidities, it can also interact with potentially painful …