Role of m6A writers, erasers and readers in cancer
Z Fang, W Mei, C Qu, J Lu, L Shang, F Cao… - … Hematology & Oncology, 2022 - Springer
Abstract The N (6)-methyladenosine (m6A) modification is the most pervasive modification of
human RNAs. In recent years, an increasing number of studies have suggested that m6A …
human RNAs. In recent years, an increasing number of studies have suggested that m6A …
The RNA-binding protein HuR in human cancer: a friend or foe?
The RNA-binding proteins (RBPs) are critical trans factors that associate with specific cis
elements present in mRNAs whose stability and translation are subject to regulation. The …
elements present in mRNAs whose stability and translation are subject to regulation. The …
[HTML][HTML] RNA binding proteins (RBPs) and their role in DNA damage and radiation response in cancer
Traditionally majority of eukaryotic gene expression is influenced by transcriptional and post-
transcriptional events. Alterations in the expression of proteins that act post-transcriptionally …
transcriptional events. Alterations in the expression of proteins that act post-transcriptionally …
HuR as a molecular target for cancer therapeutics and immune-related disorders
M Majumder, P Chakraborty, S Mohan… - Advanced drug delivery …, 2022 - Elsevier
The control of eukaryotic gene expression occurs at multiple levels, from transcription to
messenger RNA processing, transport, localization, turnover, and translation. RNA-binding …
messenger RNA processing, transport, localization, turnover, and translation. RNA-binding …
HuR controls glutaminase RNA metabolism
D Adamoski, L M. dos Reis, ACP Mafra… - Nature …, 2024 - nature.com
Glutaminase (GLS) is directly related to cell growth and tumor progression, making it a target
for cancer treatment. The RNA-binding protein HuR (encoded by the ELAVL1 gene) …
for cancer treatment. The RNA-binding protein HuR (encoded by the ELAVL1 gene) …
Biological adaptations of tumor cells to radiation therapy
A Carlos-Reyes, MA Muñiz-Lino… - Frontiers in …, 2021 - frontiersin.org
Radiation therapy has been used worldwide for many decades as a therapeutic regimen for
the treatment of different types of cancer. Just over 50% of cancer patients are treated with …
the treatment of different types of cancer. Just over 50% of cancer patients are treated with …
AU-rich element RNA binding proteins: at the crossroads of post-transcriptional regulation and genome integrity
A Sidali, V Teotia, NS Solaiman, N Bashir… - International Journal of …, 2021 - mdpi.com
Genome integrity must be tightly preserved to ensure cellular survival and to deter the
genesis of disease. Endogenous and exogenous stressors that impose threats to genomic …
genesis of disease. Endogenous and exogenous stressors that impose threats to genomic …
The multifaceted role of Fragile X-Related Protein 1 (FXR1) in cellular processes: an updated review on cancer and clinical applications
FA Khan, N Fang, W Zhang, S Ji - Cell Death & Disease, 2024 - nature.com
RNA-binding proteins (RBPs) modulate the expression level of several target RNAs (such as
mRNAs) post-transcriptionally through interactions with unique binding sites in the 3 …
mRNAs) post-transcriptionally through interactions with unique binding sites in the 3 …
Therapeutic approaches targeting molecular signaling pathways common to diabetes, lung diseases and cancer
R Raguraman, A Srivastava, A Munshi… - Advanced drug delivery …, 2021 - Elsevier
Diabetes mellitus (DM), is the most common metabolic disease and is characterized by
sustained hyperglycemia. Accumulating evidences supports a strong association between …
sustained hyperglycemia. Accumulating evidences supports a strong association between …
[HTML][HTML] Expression and prognostic values of ARID family members in breast cancer
J Zhang, S Hou, Z You, G Li, S Xu, X Li, X Zhang… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Expression and prognostic values of ARID family members in breast cancer - PMC Back to Top
Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main …
Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main …