Myricetin bioactive effects: Moving from preclinical evidence to potential clinical applications

Y Taheri, HAR Suleria, N Martins, O Sytar… - … medicine and therapies, 2020 - Springer
Several flavonoids have been recognized as nutraceuticals, and myricetin is a good
example. Myricetin is commonly found in plants and their antimicrobial and antioxidant …

Natural Products That Target Virulence Factors in Antibiotic-Resistant Staphylococcus aureus

SC Wu, F Liu, K Zhu, JZ Shen - Journal of agricultural and food …, 2019 - ACS Publications
The increase in the incidence of antibiotic-resistant Staphylococcus aureus (S. aureus)
associated infections necessitates the urgent development of novel therapeutic strategies …

Analysis of the intricate effects of polyunsaturated fatty acids and polyphenols on inflammatory pathways in health and disease

D Margină, A Ungurianu, C Purdel… - Food and chemical …, 2020 - Elsevier
Prevention and treatment of non-communicable diseases (NCDs), including cardiovascular
disease, diabetes, obesity, cancer, Alzheimer's and Parkinson's disease, arthritis, non …

The application of mesoporous silica nanoparticles as a drug delivery vehicle in oral disease treatment

L Fang, H Zhou, L Cheng, Y Wang, F Liu… - Frontiers in Cellular and …, 2023 - frontiersin.org
Mesoporous silica nanoparticles (MSNs) hold promise as safer and more effective
medication delivery vehicles for treating oral disorders. As the drug's delivery system, MSNs …

Anti-biofilm activity of biochanin A against Staphylococcus aureus

X Bai, Y Shen, T Zhang, R Meng, Y Zhang… - Applied Microbiology …, 2023 - Springer
Biofilm-forming Staphylococcus aureus can easily accumulate on various food contact
surfaces which induce cross-contamination and are difficult to eliminate in the food industry …

New pyrrole derivatives as promising biological agents: design, synthesis, characterization, in silico, and cytotoxicity evaluation

BC Ivan, SF Barbuceanu, CM Hotnog… - International Journal of …, 2022 - mdpi.com
The current study describes the synthesis, physicochemical characterization and cytotoxicity
evaluation of a new series of pyrrole derivatives in order to identify new bioactive molecules …

Myricetin as an antivirulence compound interfering with a morphological transformation into coccoid forms and potentiating activity of antibiotics against Helicobacter …

P Krzyżek, P Migdał, E Paluch, M Karwańska… - International Journal of …, 2021 - mdpi.com
Helicobacter pylori, a gastric pathogen associated with a broad range of stomach diseases,
has a high tendency to become resistant to antibiotics. One of the most important factors …

Target-based screening for natural products against Staphylococcus aureus biofilms

N Guo, X Bai, Y Shen, T Zhang - Critical Reviews in Food Science …, 2023 - Taylor & Francis
As a notorious food-borne pathogen, Staphylococcus aureus can readily cause diseases in
humans via contaminated food. Biofilm formation on various surfaces can increase the …

In-Silico Identified New Natural Sortase A Inhibitors Disrupt S. aureus Biofilm Formation

KRV Thappeta, LN Zhao, CE Nge, S Crasta… - International Journal of …, 2020 - mdpi.com
Sortase A (SrtA) is a membrane-associated enzyme that anchors surface-exposed proteins
to the cell wall envelope of Gram-positive bacteria such as Staphylococcus aureus. As SrtA …

Targeting bacterial sortases in search of anti-virulence therapies with low risk of resistance development

G Nitulescu, D Margina, A Zanfirescu, OT Olaru… - Pharmaceuticals, 2021 - mdpi.com
Increasingly ineffective antibiotics and rapid spread of multi-and pan-resistant bacteria
represent a global health threat; hence, the need of developing new antimicrobial …