Machine learning in bioprocess development: from promise to practice
Fostered by novel analytical techniques, digitalization, and automation, modern bioprocess
development provides large amounts of heterogeneous experimental data, containing …
development provides large amounts of heterogeneous experimental data, containing …
When bioprocess engineering meets machine learning: A survey from the perspective of automated bioprocess development
N Duong-Trung, S Born, JW Kim… - Biochemical …, 2023 - Elsevier
Abstract Machine learning (ML) is becoming increasingly crucial in many fields of
engineering but has not yet played out its full potential in bioprocess engineering. While …
engineering but has not yet played out its full potential in bioprocess engineering. While …
[HTML][HTML] Combining multi-fidelity modelling and asynchronous batch Bayesian Optimization
Bayesian Optimization is a useful tool for experiment design. Unfortunately, the classical,
sequential setting of Bayesian Optimization does not translate well into laboratory …
sequential setting of Bayesian Optimization does not translate well into laboratory …
[HTML][HTML] Digitally enabled approaches for the scale up of mammalian cell bioreactors
MK Alavijeh, I Baker, YY Lee, SL Gras - Digital Chemical Engineering, 2022 - Elsevier
With recent advances in digitisation and big data analytics, more pharmaceutical firms are
adopting digital tools to achieve modernisation. The biological phenomena within …
adopting digital tools to achieve modernisation. The biological phenomena within …
Developing high-dimensional machine learning models to improve generalization ability and overcome data insufficiency for mixed sugar fermentation simulation
Biorefinery can be promoted by building accurate machine learning models. This work
proposed a strategy to enhance model's generalization ability and overcome insufficient …
proposed a strategy to enhance model's generalization ability and overcome insufficient …
[HTML][HTML] Applications of machine learning in antibody discovery, process development, manufacturing and formulation: Current trends, challenges, and opportunities
TT Khuat, R Bassett, E Otte, A Grevis-James… - Computers & Chemical …, 2024 - Elsevier
While machine learning (ML) has made significant contributions to the biopharmaceutical
field, its applications are still in the early stages in terms of providing direct support for quality …
field, its applications are still in the early stages in terms of providing direct support for quality …
Deep learning radiomics for the assessment of telomerase reverse transcriptase promoter mutation status in patients with glioblastoma using multiparametric MRI
H Zhang, H Zhang, Y Zhang, B Zhou… - Journal of Magnetic …, 2023 - Wiley Online Library
Background Studies have shown that magnetic resonance imaging (MRI)‐based deep
learning radiomics (DLR) has the potential to assess glioma grade; however, its role in …
learning radiomics (DLR) has the potential to assess glioma grade; however, its role in …
[HTML][HTML] A review and perspective on hybrid modelling methodologies
The term hybrid modeling refers to the combination of parametric models (typically derived
from knowledge about the system) and nonparametric models (typically deduced from data) …
from knowledge about the system) and nonparametric models (typically deduced from data) …
A comparative evaluation of machine learning algorithms for predicting syngas fermentation outcomes
Clostridium carboxidivorans can use syngas to produce acids and alcohols. However,
simulating gas fermentation dynamics remains challenging. This study employed data …
simulating gas fermentation dynamics remains challenging. This study employed data …
A monitoring method for surface roughness of γ-TiAl alloy based on deep learning of time–frequency diagram
Y Wu, L Liu, L Huang, Z Wang - The International Journal of Advanced …, 2023 - Springer
Abstract γ-TiAl alloy is a typically difficult material to machine, with common machining
defects such as grain pull-out and material spalling during machining, resulting in …
defects such as grain pull-out and material spalling during machining, resulting in …