Cancer remains an elusive, highly complex disease and a global burden. Constant change
by acquired mutations and metabolic reprogramming contribute to the high inter-and …

Glioblastoma (GB) is a primary malignancy of the central nervous system that is classified by
the WHO as a grade IV astrocytoma. Despite decades of research, several aspects about the …

The head and neck squamous cell carcinoma (HNSCC) is one of the most common cancers
in the world, but robust biomarkers and diagnostics are still not available. This study …

Astrocytic tumors are known for their high progression capacity and high mortality rates; in
this regard, proteins correlated to prognosis can aid medical conduct. Although several …

The emergence of omics technologies over the last decade has helped in advancement of
research and our understanding of complex diseases like brain cancers. However, barring …

Glioblastoma is a highly malignant cancer with no effective treatment. It is vital to elucidate
the mechanisms which drive glioblastoma in order to identify therapeutic targets. The …

Background Lycorine has been revealed to inhibit the development of many kinds of
malignant tumors, including glioblastoma multiforme (GBM). Although compelling evidences …

The thioredoxin (Trx) system is an important enzyme family that regulates cellular redox
homeostasis. Protein expression of Trx system family members has been assessed in …

Thioredoxin (Trx) overexpression is known to be a cause of chemotherapy resistance in
various tumor entities. However, Trx effects on resistance are complex and depend strictly …

Introduction: Despite being rare cancers, gliomas account for a significant number of cancer-
related deaths. Identification and treatment of these tumors at an early stage would greatly …