The incorporation of a synthetic, catalytically competent metallocofactor into a protein
scaffold to generate an artificial metalloenzyme (ArM) has been explored since the late …

Defined-sequence polymers have great potential as durable and high-density data-storage
media. DNA already fulfils this role in nature, using the sequence of its four nucleobases to …

Biomolecular motors convert energy into directed motion and operate away from thermal
equilibrium. The development of dynamic chemical systems that exploit dissipative (non …

Mechanically interlocked molecules have a long and rich history as ligands thanks to the key
role coordination chemistry has played in the development of high yielding passive template …

Rotaxanes are molecules composed of one or more macrocycles threaded onto one or more
axles that bear bulky stoppers to prevent the macrocycles from slipping off. 1 The first …

Biomolecular machines perform types of complex molecular-level tasks that artificial
molecular machines can aspire to. The ribosome, for example, translates information from …

The past quarter of a century has witnessed an increasing engagement on the part of
physicists and chemists in the design and synthesis of molecular machines de novo. This …

Mechanical point-chirality in a [2] rotaxane is utilized for asymmetric catalysis. Stable
enantiomers of the rotaxane result from a bulky group in the middle of the thread preventing …

The past few decades have seen tremendous progress in the synthesis and operation of
molecular systems capable of controlled mechanical movement. Here, we review the use of …

A rotaxane‐based Au catalyst was developed and the effect of the mechanical bond on its
behavior was studied. Unlike the non‐interlocked thread, the rotaxane requires a …