Environmentally induced epigenetic transgenerational inheritance of disease

EE Nilsson, I Sadler-Riggleman… - Environmental …, 2018 - academic.oup.com
Ancestral environmental exposures such as toxicants, abnormal nutrition or stress can
promote the epigenetic transgenerational inheritance of disease and phenotypic variation …

Transgenerational plasticity and climate change experiments: Where do we go from here?

JM Donelson, S Salinas, PL Munday… - Global Change …, 2018 - Wiley Online Library
Phenotypic plasticity, both within and across generations, is an important mechanism that
organisms use to cope with rapid climate change. While an increasing number of studies …

Evolution of heat‐shock protein expression underlying adaptive responses to environmental stress

B Chen, ME Feder, L Kang - Molecular ecology, 2018 - Wiley Online Library
Heat‐shock proteins (Hsps) and their cognates are primary mitigators of cell stress. With
increasingly severe impacts of climate change and other human modifications of the …

On the maintenance of genetic variation and adaptation to environmental change: considerations from population genomics in fishes

L Bernatchez - Journal of Fish Biology, 2016 - Wiley Online Library
The first goal of this paper was to overview modern approaches to local adaptation, with a
focus on the use of population genomics data to detect signals of natural selection in fishes …

[HTML][HTML] Innate immune memory in invertebrate metazoans: a critical appraisal

D Melillo, R Marino, P Italiani, D Boraschi - Frontiers in Immunology, 2018 - frontiersin.org
The ability of developing immunological memory, a characteristic feature of adaptive
immunity, is clearly present also in innate immune responses. In fact, it is well known that …

Epigenetic transgenerational inheritance of obesity susceptibility

SE King, MK Skinner - Trends in Endocrinology & Metabolism, 2020 - cell.com
The prevalence of obesity and associated diseases has reached pandemic levels. Obesity is
often associated with overnutrition and a sedentary lifestyle, but clearly other factors also …

DNA methylation mediates genetic variation for adaptive transgenerational plasticity

JJ Herman, SE Sultan - … of the Royal Society B: Biological …, 2016 - royalsocietypublishing.org
Environmental stresses experienced by individual parents can influence offspring
phenotypes in ways that enhance survival under similar conditions. Although such adaptive …

Endocrine disruptor induction of epigenetic transgenerational inheritance of disease

MK Skinner - Molecular and cellular endocrinology, 2014 - Elsevier
Environmental exposures such as toxicants, nutrition and stress have been shown to
promote the epigenetic transgenerational inheritance of disease susceptibility. Endocrine …

Lamarck rises from his grave: parental environment‐induced epigenetic inheritance in model organisms and humans

Y Wang, H Liu, Z Sun - Biological Reviews, 2017 - Wiley Online Library
Organisms can change their physiological/behavioural traits to adapt and survive in
changed environments. However, whether these acquired traits can be inherited across …

Developmental origins of epigenetic transgenerational inheritance

MA Hanson, MK Skinner - Environmental epigenetics, 2016 - academic.oup.com
Environmental factors can induce epigenetic alterations in the germ cells that can potentially
be transmitted transgenerationally. This non-genetic form of inheritance is termed epigenetic …