Alcohol is one of the most widely consumed psychoactive drugs globally. Hazardous
drinking, defined by quantity and frequency of consumption, is associated with acute and …

Opioid use disorder (OUD) is a chronic relapsing disorder that, whilst initially driven by
activation of brain reward neurocircuits, increasingly engages anti-reward neurocircuits that …

On October 30 and 31, 2018, the Committee on Medication-Assisted Treatment (MAT) for
Opioid Use Disorder (OUD) held a 1.5-day workshop in Washington, DC. To support the …

Deeming prescription-opioid overdoses an epidemic, the Department of Health and Human
Services is working to reduce opioid abuse while ensuring appropriate access to opioids …

Objectives. To estimate health outcomes of policies to mitigate the opioid epidemic.
Methods. We used dynamic compartmental modeling of US adults, in various pain, opioid …

The prevalence of opioid use and misuse has provoked a staggering number of deaths over
the past two and a half decades. Much attention has focused on individual risks according to …

Background and aims Evidence from randomized controlled trials establishes that
medication treatment with methadone and buprenorphine reduces opioid use and improves …

Medication treatment (MT) is one of the few evidence-based strategies proposed to combat
the current opioid epidemic. We examined national trends and correlates of offering MT in …

Prescription opioid abuse and addiction, along with consequences such as overdose death
and increasing transition to heroin use, constitute a devastating public health problem in the …

Abstract Background Kratom is a South Eastern Asian tree whose leaves are used to make
tea-like brews or swallowed in powdered form for various health and well-being reasons …