Biolayer interferometry for measuring the kinetics of protein–protein interactions and nanobody binding
TA Bates, SK Gurmessa, JB Weinstein… - Nature protocols, 2024 - nature.com
Protein–protein interactions underpin nearly all biological processes, and understanding the
molecular mechanisms that govern these interactions is crucial for the progress of …
molecular mechanisms that govern these interactions is crucial for the progress of …
Antibodies as key mediators of protection against Mycobacterium tuberculosis
Q Wang, D Nag, SL Baldwin, RN Coler… - Frontiers in …, 2024 - frontiersin.org
Tuberculosis (TB) is caused by infection with the bacterial pathogen Mycobacterium
tuberculosis (M. tb) in the respiratory tract. There was an estimated 10.6 million people …
tuberculosis (M. tb) in the respiratory tract. There was an estimated 10.6 million people …
Antigen specificity shapes antibody functions in tuberculosis
JR Miles, P Lu, S Bai, GP Aguillón-Durán… - …, 2024 - pmc.ncbi.nlm.nih.gov
Tuberculosis (TB) is the number one infectious disease cause of death worldwide due to an
incomplete understanding of immunity. Emerging data highlight antibody functions mediated …
incomplete understanding of immunity. Emerging data highlight antibody functions mediated …
Real-time visualization reveals Mycobacterium tuberculosis ESAT-6 disrupts phagosome via fibril-mediated vesiculation
Mycobacterium tuberculosis (Mtb) evades host defense by hijacking and rupturing the
phagosome, enabling it to escape to the host cytosol for its survival. ESAT-6, a secreted …
phagosome, enabling it to escape to the host cytosol for its survival. ESAT-6, a secreted …