Diabetic vascular diseases: molecular mechanisms and therapeutic strategies
Y Li, Y Liu, S Liu, M Gao, W Wang, K Chen… - Signal transduction and …, 2023 - nature.com
Vascular complications of diabetes pose a severe threat to human health. Prevention and
treatment protocols based on a single vascular complication are no longer suitable for the …
treatment protocols based on a single vascular complication are no longer suitable for the …
Obesity and cardiovascular disease: mechanistic insights and management strategies. A joint position paper by the World Heart Federation and World Obesity …
F Lopez-Jimenez, W Almahmeed… - European journal of …, 2022 - academic.oup.com
The ongoing obesity epidemic represents a global public health crisis that contributes to
poor health outcomes, reduced quality of life, and> 2.8 million deaths each year. Obesity is …
poor health outcomes, reduced quality of life, and> 2.8 million deaths each year. Obesity is …
Treatment effect heterogeneity following type 2 diabetes treatment with GLP1-receptor agonists and SGLT2-inhibitors: a systematic review
KG Young, EH McInnes, RJ Massey… - Communications …, 2023 - nature.com
Background A precision medicine approach in type 2 diabetes requires the identification of
clinical and biological features that are reproducibly associated with differences in clinical …
clinical and biological features that are reproducibly associated with differences in clinical …
Sodium‐glucose cotransporter 2 inhibitor canagliflozin antagonizes salt‐sensitive hypertension through modifying transient receptor potential channels 3 mediated …
Y Zhao, L Li, Z Lu, Y Hu, H Zhang, F Sun… - Journal of the …, 2022 - Am Heart Assoc
Background Salt‐sensitive hypertension is highly prevalent and associated with cardiorenal
damage. Large clinical trials have demonstrated that SGLT2 (sodium‐glucose cotransporter …
damage. Large clinical trials have demonstrated that SGLT2 (sodium‐glucose cotransporter …
Preclinical modeling of metabolic syndrome to study the pleiotropic effects of novel antidiabetic therapy independent of obesity
Cardiovascular-kidney-metabolic health reflects the interactions between metabolic risk
factors, chronic kidney disease, and the cardiovascular system. A growing body of literature …
factors, chronic kidney disease, and the cardiovascular system. A growing body of literature …
Quételet (body mass) index and effects of dapagliflozin in chronic kidney disease
Aim To assess the effects of dapagliflozin in patients with chronic kidney disease (CKD) and
albuminuria, with and without type 2 diabetes, stratified by the Quételet (body mass) index …
albuminuria, with and without type 2 diabetes, stratified by the Quételet (body mass) index …
Diabetes status modifies the association between different measures of obesity and heart failure risk among older adults: a pooled analysis of community-based …
Background: Obesity and diabetes are associated with a higher risk of heart failure (HF). The
interrelationships between different measures of adiposity—overall obesity, central obesity …
interrelationships between different measures of adiposity—overall obesity, central obesity …
[HTML][HTML] Precision medicine in type 2 diabetes: A systematic review of treatment effect heterogeneity for GLP1-receptor agonists and SGLT2-inhibitors
Background: A precision medicine approach in type 2 diabetes requires identification of
clinical and biological features that are reproducibly associated with differences in clinical …
clinical and biological features that are reproducibly associated with differences in clinical …
Therapeutic repurposing of antidiabetic drugs in diabetes-associated comorbidities
Background: Diabetic patients suffer from various comorbidities like cardiovascular diseases
(CVDs), cancer, obesity, cognitive impairment, gout, leishmaniasis, etc. Objective: We aimed …
(CVDs), cancer, obesity, cognitive impairment, gout, leishmaniasis, etc. Objective: We aimed …
Epidemiology and treatment of acute and chronic heart failure
F Crea - European Heart Journal, 2023 - academic.oup.com
Boer; 1 'The year in cardiovascular medicine 2022: the top 10 papers in arrhythmias'
authored by Harry JGM Crijns, Pier Lambiase, and Prash Sanders; 2 and 'The year in …
authored by Harry JGM Crijns, Pier Lambiase, and Prash Sanders; 2 and 'The year in …