With approximately 160,000 identified species of butterflies and moths, Lepidoptera are
among the most species-rich and diverse insect orders. Lepidopteran insects have …

After a slow start, the comparative analysis of clock genes in insects has developed into a
mature area of study in recent years. Brain transplant or surgical interventions in larger …

The winter moth (Operophtera brumata) belongs to one of the most species-rich families in
Lepidoptera, the Geometridae (approximately 23,000 species). This family is of great …

Periodic expression of so-called clock genes is an essential part of the circadian clock. In
Drosophila melanogaster the cyclic expression of per and tim through an autoregulatory …

RNA interference (RNAi) suppresses the expression of target genes by post‐transcriptional
regulation. Because double‐stranded RNA (dsRNA) mediated gene silencing is a …

The domesticated silkworm, Bombyx mori, is a fundamental insect for silk industry. Silk is
obtained from cocoons, protective envelopes produced during pupation and composed of …

Numerous and charismatic, the Lepidoptera is one of the most widely studied groups of
invertebrates. Advances in molecular tools and genomic techniques have reduced the need …

In Lepidoptera, the roles of period (per) and the negative feedback involving this gene in
circadian rhythm are controversial. In the present study, we established a per knockout strain …

Copy number gain in chromosome 8q21 is frequently detected in breast cancer, yet the
oncogenic potential underlying this amplicon in breast carcinogenesis remains to be …

The period (per) gene is 1 of the core elements of the circadian clock mechanism in animals
from insects to mammals. In clock cells of Drosophila melanogaster, per mRNA and PER …