Importance of the field: Vascular delivery of several classes of therapeutic agents may
benefit from carriage by red blood cells (RBC), for example, drugs that require delivery into …

Carrier erythrocytes, resealed erythrocytes loaded by a drug or other therapeutic agents,
have been exploited extensively in recent years for both temporally and spatially controlled …

Exogenous insulin (INS) is critical for managing diabetes. However, owing to its short in vivo
half-life, frequent injection of INS is un-avoidable, which is both painful and inconvenient …

Novel drug delivery systems are one of the widely used delivery systems. In the present
scenario, amongst them,“Drug Loaded Erythrocytes” is one of the growing and potential …

Red blood cells (RBCs) are the most abundant cell type in the blood, and play a critical role
in oxygen transport. With the development of nanobiotechnology and synthetic biology …

Insulin (INS) delivery system that can mimic normal insulin secretion to maintain the blood
glucose level (BGL) in the normal range is an ideal treatment for diabetes. However, most of …

Diabetes mellitus is a serious pathologic condition that is responsible for major healthcare
problems worldwide and costing billions of dollars annually. Insulin replacement therapy …

As the use of engineered cell therapies expands from pioneering efforts in cancer
immunotherapy to other applications, an attractive but less explored approach is the use of …

In our study, molecular docking and molecular dynamics (MD) simulations were performed
in order to explore the interactions between human insulin and β-cyclodextrin (β-CD) …

Background: To investigate pharmacokinetics and potency of antitumor activity of a novel 5‐
fluorouracil carrier erythrocyte (RBC‐FU) in mice bearing malignant ascites. Methods: RBC …