Natural pentacyclic triterpenoids (PTs) have been often reported to exhibit a wide range of
biological activities. Among them, the anticancer and anti-inflammatory activities are the …

Secondary insult from cerebral ischemia-reperfusion injury (CIRI) is a major risk factor for
poor prognosis of cerebral ischemia. Saponins are steroid or triterpenoid glycosides with …

Exosomes are nano-extracellular vesicles with diameters ranging from 30 to 150 nm, which
are secreted by the cell. With their role in drug cargo loading, exosomes have been applied …

Background: Sarcocephalus pobeguinii (Hua ex Pobég) is used in folk medicine to treat
oxidative-stress related diseases, thereby warranting the investigation of its anticancer and …

Cerebral ischaemia/reperfusion (CI/R) injury is a major challenge due to the lack of effective
neuroprotective drugs. Hederagenin (HE) is the aglycone part of saponins extracted from …

Clematis mandshurica Ruprecht root has been used in Asia as a traditional anti-
inflammatory, analgesic, and antitumor agent. Its main active component is hederagenin, a …

Background Colorectal cancer has become one of the leading cause of cancer morbidity
and mortality throughout world. Hederagenin, a derivative of oleanolic acid isolated from the …

Covering: 2012. Previous review: Nat. Prod. Rep., 2013, 29, 1028–1065 This review covers
the isolation and structure determination of triterpenoids reported during 2012 including …

An ethanol extract prepared from the leaves of Cyclocarya paliurus, also known as sweet
tea, which is one of the most popular teas utilized in traditional Chinese medicine, exhibited …

The aim of this research was to discuss Hederagenin's antitumor effects on glioma by in vitro
study. U251 and U87 cell lines were used as research target in our research. In the first step …