Monoclonal gammopathy of clinical significance: a novel concept with therapeutic implications

JP Fermand, F Bridoux, A Dispenzieri… - Blood, The Journal …, 2018 - ashpublications.org
Monoclonal gammopathy is a common condition, particularly in the elderly. It can indicate
symptomatic multiple myeloma or another overt malignant lymphoid disorder requiring …

[HTML][HTML] Fatal exacerbations of systemic capillary leak syndrome complicating coronavirus disease

PC Cheung, AR Eisch, N Maleque… - Emerging Infectious …, 2021 - ncbi.nlm.nih.gov
We report 2 fatal exacerbations of systemic capillary leak syndrome (SCLS), also known as
Clarkson disease, associated with coronavirus disease (COVID-19) in the United States …

Intrinsic endothelial hyperresponsiveness to inflammatory mediators drives acute episodes in models of Clarkson disease

AJ Ablooglu, WS Chen, Z Xie, A Desai… - The Journal of …, 2024 - Am Soc Clin Investig
Clarkson disease, or monoclonal gammopathy–associated idiopathic systemic capillary leak
syndrome (ISCLS), is a rare, relapsing-remitting disorder featuring the abrupt extravasation …

Clinical presentation, management, and prognostic factors of idiopathic systemic capillary leak syndrome: a systematic review

TS Eo, KJ Chun, SJ Hong, JY Kim, IR Lee… - The Journal of Allergy …, 2018 - Elsevier
Background The idiopathic systemic capillary leak syndrome is a rare disease characterized
by unexplained recurrent shock caused by capillary hyperpermeability. Because of the rarity …

[HTML][HTML] Anticancer drug-induced capillary leak syndrome

H Izzedine, A Mathian, Z Amoura, JH Ng… - Kidney International …, 2022 - Elsevier
The term capillary leak syndrome (CLS) describes the manifestations associated with an
increased capillary permeability to proteins leading to an escape of plasma from the blood …

Severe exacerbations of systemic capillary leak syndrome after COVID-19 vaccination: a case series

M Matheny, N Maleque, N Channell… - Annals of Internal …, 2021 - acpjournals.org
Background: Flares of systemic capillary leak syndrome (SCLS) release plasma into
peripheral tissues, which typically leads to hypotensive shock and multiple organ …

Monoclonal gammopathies of clinical significance (MGCS): In pursuit of optimal treatment

A Oganesyan, A Gregory, F Malard… - Frontiers in …, 2022 - frontiersin.org
Monoclonal gammopathy of clinical significance (MGCS) represents a new clinical entity
referring to a myriad of pathological conditions associated with the monoclonal gammopathy …

[PDF][PDF] SARS-CoV-2 induces acute and refractory relapse of systemic capillary leak syndrome (Clarkson's disease)

MP de Chambrun, F Cohen-Aubart, DW Donker… - The American journal of …, 2020 - Elsevier
The systemic capillary-leak syndrome (SCLS), also known as Clarkson's disease, is a 3 rare
condition characterized by recurrent episodes of capillary hyperpermeability in the 4 context …

Capillary leak syndrome: State of the art in 2021

A Bichon, J Bourenne, M Gainnier, J Carvelli - La Revue de Médecine …, 2021 - Elsevier
Capillary leak syndrome (CLS) is an increasingly acknowledged multifaceted and potentially
lethal disease. Initial nonspecific symptoms are followed by the intriguing CLS hallmark: the …

Systemic capillary leak syndrome (SCLS) after receiving BNT162b2 mRNA COVID-19 (Pfizer-BioNTech) vaccine

M Inoue, Y Yasue, Y Kobayashi… - BMJ Case Reports …, 2022 - casereports.bmj.com
Systemic capillary leak syndrome (SCLS), also known as Clarkson's disease, is a rare
disorder of unknown aetiology. Since SCLS was first described in 1960, fewer than 500 …