MicroRNAs (miRNAs) are small, non-coding RNAs that post-transcriptionally regulate gene
expression by binding to specific mRNA targets and promoting their degradation and/or …

Aim and objective Emerging translational evidence suggests that epigenetic alterations
(DNA methylation, miRNA expression, and histone modifications) occur after external stimuli …

Alcoholic liver disease (ALD) is the most prevalent type of chronic liver disease worldwide.
ALD can progress from alcoholic fatty liver (AFL) to alcoholic steatohepatitis (ASH), which is …

Alcohol use disorder (AUD) is a widespread disease with limited treatment options.
Targeting the neuroimmune system is a new avenue for developing or repurposing effective …

Alcohol is inextricably linked with the digestive system. It is absorbed through the gut and
metabolised by hepatocytes within the liver. Excessive alcohol use results in alterations to …

Alcohol-related liver disease (ALD) refers to the liver damage occurring due to excessive
alcohol consumption and involves a broad spectrum of diseases that includes liver steatosis …

Chronic alcohol consumption is linked to the development of alcohol-associated liver
disease (ALD). This disease is characterized by a clinical spectrum ranging from steatosis to …

Epigenetic mechanisms, such as acetylation, methylation, and succinylation, play pivotal
roles in the regulation of multiple normal biological processes, including neuron regulation …

MicroRNAs (miRNAs) are critical mediators of posttranscriptional regulation via their
targeting of the imperfect antisense complementary regions of coding and non-coding …

Drinking alcohol, even in moderation, can affect the immune system. Studies have shown
disproportionate effects of alcohol on circulating and tissue-resident myeloid cells …