The effects of current treatment strategies for ischemic stroke are weakened by ischemia-
reperfusion (I/R) injury. Effective treatments targeting I/R injury are still insufficient …

Rodents are the most widely used experimental animals in stroke research due to their
similar vascular anatomy, high reproductive rates, and availability of transgenic models …

Background Neuroinflammation is closely associated with the poor prognosis in
subarachnoid hemorrhage (SAH) patients. This study was aimed to determine the role of …

Hemostatic sealant is required to deal with blood loss, especially in the scenario of traumatic
brain injury (TBI), which presents high rates of morbidity and disability. Hemostasis in …

The infiltration of blood components into the brain parenchyma through the lymphoid system
is an important cause of subarachnoid hemorrhage injury. AQP4, a water channel protein …

Aims: Metabolic disorders may play key roles in oxidative stress and neuronal apoptosis in
response to early brain injury (EBI) after subarachnoid hemorrhage (SAH). Pyruvate …

The glymphatic system (GS) plays an important role in subarachnoid hemorrhage (SAH).
Nimodipine treatment provides SAH patients with short-term neurological benefits. However …

Background: Although early brain injury (EBI) is recognized as a critical step following
subarachnoid hemorrhage (SAH), its pathophysiology and underlying mechanisms remain …

The production of reactive oxygen species (ROS) during and after the onset of an ischemic
stroke induces neuronal cell death and severely damages brain function. Therefore …

Early brain injury (EBI) has been recognized as a major cause of poor clinical outcomes in
patients with spontaneous subarachnoid hemorrhage (SAH). Endoplasmic reticulum (ER) …