Cancer metastasis is a major reason for the cancer-associated deaths and a role of long non-
coding RNAs (lncRNAs) in cancer metastasis is increasingly being realized. Among the …

Cancer is driven by genetic mutations in oncogenes and tumor suppressor genes and by
cellular events that develop a misregulated molecular microenvironment in the growing …

TGF‐β plays a central role in mediating epithelial–mesenchymal transition (EMT) by
activating the Smad pathway. In addition, accumulating evidence suggests that TGF‐β …

Cancer‐associated fibroblasts (CAF) are a heterogeneous cell population within the tumor
microenvironment, and play an important role in tumor development. By regulating the …

Abstract Desmoglein-2 (DSG2), a member of the cadherin superfamily, has been implicated
in cell-cell adhesion and tumorigenesis. Here, we demonstrate that high DSG2 expression …

Objective The relationship between NF-κB Interacting lncRNA (NKILA) and angiogenesis in
breast cancer has never been studied. Our study aimed to investigate effect of NKILA on …

Transforming growth factor-β (TGF-β) is a crucial pathogenic mediator of inflammatory
diseases. In tissue fibrosis, TGF-β regulates the pathogenic activity of infiltrated …

Background Esophageal squamous cell carcinoma (ESCC) has a poor prognosis and is one
of the deadliest gastrointestinal malignancies. Despite numerous transcriptomics studies to …

Background Current strategies are insufficient to predict pathologically complete response
(pCR) for esophageal squamous cell carcinomas (ESCCs) before treatment. Here, we aim to …

Long non-coding RNAs (lncRNAs) are regarded as a group of biomarkers in the initiation
and development of various cancers, including hepatocellular carcinoma (HCC). LncRNA …