Understanding the evolutionary and ecological roles of'non-genetic'inheritance (NGI) is
daunting due to the complexity and diversity of epigenetic mechanisms. We draw on insights …

The basic vertebrate body plan of the zebrafish embryo is established in the first 10 hours of
development. This period is characterized by the formation of the anterior-posterior and …

During the maternal-to-zygotic transition (MZT), multiple mechanisms precisely control
massive decay of maternal mRNAs. N 6-methyladenosine (m 6 A) is known to regulate …

Tissue morphogenesis is driven by mechanical forces that elicit changes in cell size, shape
and motion. The extent by which forces deform tissues critically depends on the rheological …

The production of fertile eggs with the capacity to develop into larvae and subsequently into
marketable fish is centrally important to the aquaculture industry. This entails not only the …

Zebrafish (Danio rerio) is a well-recognized model for the study of vertebrate developmental
genetics, yet at the same time little is known about the transcriptional events that underlie …

The development of facile forward and reverse genetic approaches has propelled the
deconvolution of gene function in biology. While the origins of these techniques reside in the …

Over the last decade, the use of the zebrafish as a genetic model has moved beyond the
proof-of-concept for the analysis of vertebrate embryonic development to demonstrated …

Maternal factors control development prior to the activation of the embryonic genome. In
vertebrates, little is known about the molecular mechanisms by which maternal factors …

The earliest stages of embryonic development in all animals examined rely on maternal
gene products that are generated during oogenesis and supplied to the egg. The period of …