• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

The autonomic nervous system (ANS) and the immune system are deeply interrelated. The
ANS regulates both innate and adaptive immunity through the sympathetic and …

Systemic lupus erythematosus (SLE) is an autoimmune disease that has diverse clinical
manifestations, ranging from restricted cutaneous involvement to life-threatening systemic …

Background Systemic lupus erythematosus (SLE) is an autoimmune disease that typically
affects women aged 16–55 years. Cardiovascular disease (CVD) is a well-recognized …

Autoimmune diseases are associated with a dramatically increased risk of atherosclerotic
cardiovascular disease and its clinical manifestations. The increased risk is consistent with …

Even though diagnosis and management pathways have been substantially improved over
the last years, autoimmune rheumatic diseases (AIRDs) such as rheumatoid arthritis (RA) …

Background The use of immune checkpoint inhibitors (ICI) is associated with cardiovascular
(CV) events, and patients with pre-existing autoimmune disease are at increased CV risk …

Objectives To perform a systematic literature review and meta-analysis on endothelial cell
(EC) markers that are involved and dysregulated in systemic lupus erythematosus (SLE) in …

Abstract Treat-to-target (T2T) is currently the most fashionable strategy for treatment-naïve,
early rheumatoid arthritis (RA) patients. A T2T approach can lead to a complete and drug …

Many epidemiological studies have shown an increased risk of venous thromboembolism
(VTE) in patients with rheumatoid arthritis (RA). RA and VTE share some background …